Two things to know for melasma (chloasma, mask of pregnancy) initial treatment consists of topical application (in addition to sun protection): The use of hydroquinone creams combining Vitamin-A-steroids makes the laser treatment more effective if it has not been used. It is advisable to use a topical treatment as much as possible before using the…
Two things to know for melasma (chloasma, mask of pregnancy) initial treatment consists of topical application (in addition to sun protection): The use of hydroquinone creams combining Vitamin-A-steroids makes the laser treatment more effective if it has not been used. It is advisable to use a topical treatment as much as possible before using the…
As a general rule when treating pigment disorders with lasers, the following apply: It is important to recognize that we treat Always biopsy a suspicious lesion Know the alternative treatments Practical rules for treating pigmentation disorders Avoid aggravating factors (sun, irritating …) Do nothing for problems of pigmentation that heal on their own Treat problems…
Treatments in use and their evidence in the treatment of Melasma (Chloasma) (Pregnancy Mask) Evidence is classified from A (the best with the most evidence) to E A 4% hydroquinone + 0.05% retinoic acid (RA) + 0.01% fluocinolone acetonide B 4% hydroquinone (HQ) 0.1% tretinoin (RA) 2% HQ + 0.05% RA + 0.1% dexamethasone (Modified…
New Depigmenting substances: N-acetyl glucosamine Artocarpanone 4-n-butylresorcinol (rucinol) Ursolic Acid Anthraquinones Cinnamic Acid Macelignan Gallic Acid Glycine Isopanduratin A and 4-Hydroxypanduratin A Kurarinol, Kurarinidol and Trifolirhizin Pycnogenol 8% topical indomethacin cream Selina dien-8-one Taxifolin DeoxyArbutin and its second generation derivatives Hydroperoxy Traxastane t; type Triterpene Piceatannol Handog E. Brown Spots: Melasma Updates.2012 (02) – 20th…
New Depigmenting substances: N-acetyl glucosamine Artocarpanone 4-n-butylresorcinol (rucinol) Ursolic Acid Anthraquinones Cinnamic Acid Macelignan Gallic Acid Glycine Isopanduratin A and 4-Hydroxypanduratin A Kurarinol, Kurarinidol and Trifolirhizin Pycnogenol 8% topical indomethacin cream Selina dien-8-one Taxifolin DeoxyArbutin and its second generation derivatives Hydroperoxy Traxastane t; type Triterpene Piceatannol Handog E. Brown Spots: Melasma Updates.2012 (02) – 20th…
Prevention: primary: no vaccine available Vaccination against tuberculosis (TBC) also called BCG (Bacille Calmette Guerin against tuberculosis) has some effect secondary=early diagnosis and treatment: chemoprophylaxis (treatment of subclinical leprosy) (destined to those in potential contact) and immunoprophylaxis: single dose of rifampicine 300mg-600mg according to weight tertiary: prevention of disability leprosy (Hansen’s Disease) and TBC BCG…
Epidemiology: cause: mycobacterium leprae reservoir in humans, (and a few animals such as the nine-banded armadillo) transmission by inhalation (respiratory) (also by skin contact) Development of the disease through T-cell mediated response Less than 5% of people are infected in an affected group (attack rate) less than 5%, death is lower than 0.1% Incubation period…
They act through: Tyrosinase Inhibition Inhibitors of Inflammation-induced Melanogenic Response Peroxidase inhibition Product Reduction and ROS (Radical Oxygen Scavengers) Tyrosinase inhibition hydroquinone 4-hydroxyanisole 4-S-CAP and derivatives Arbutin Aloesin Azelaic Acid Kojic Acid Ellagic Acid Resveratrol Oxyeresveratrol Licorice Extract Lactic Acid Inhibitors of Inflammation Induced Melanogenic Response Chamomille Corticosteroids Gliabridin Tranexamic Acid Peroxidase…
Skin color is determined by: The type of melanin The amount of melanin in melanocytes The distribution pattern in surrounding keratinocytes The term melasma comes from Greek melas: black Etiology: The exact cause is unknown but some factors play a role Ultraviolet light (UV) genetic factors thyroid disturbances cosmetics hormonal factors (in females) Epidemiology…
