Review of treatment options for psoriasis in pregnant or lactating women: from the Medical Board of the National Psoriasis Foundation. Bae YS, Van Voorhees AS, Hsu S, Korman NJ, Lebwohl MG, Young M, Bebo B Jr, Kimball AB; National Psoriasis Foundation. J Am Acad Dermatol. 2012 Sep;67(3):459-77. doi: 10.1016/j.jaad.2011.07.039. Epub 2011 Oct 22. Review. Psoriasis…
DetailsUV-mediated downregulation of the endocytic collagen receptor, Endo180, contributes to accumulation of extracellular collagen fragments in photoaged skin. Tang S, Lucius R, Wenck H, Gallinat S, Weise JM. J Dermatol Sci. 2013 Apr;70(1):42-8. doi: 10.1016/j.jdermsci.2013.01.008. Epub 2013 Feb 4. Skin aging can be divided into two parts: intrinsic aging or the passing of years. Nothing…
DetailsA randomized double-blind placebo-controlled pilot study to assess the efficacy of a 24-week topical treatment by latanoprost 0.1% on hair growth and pigmentation in healthy volunteers with androgenetic alopecia. Blume-Peytavi U, Lönnfors S, Hillmann K, Garcia Bartels N. J Am Acad Dermatol. 2012 May;66(5):794-800. doi: 10.1016/j.jaad.2011.05.026. Epub 2011 Aug 27. Hair loss is most commonly…
DetailsLupus Erythematosus and the Skin (For Professionals) Have you heard about Lupus Erythematosus (LE)? This is an autoimmune disorder which is caused by antibodies against the nucleus of cells. They are usually found in women aged 20 to 50, but males can also be affected. It is a systemic disorder (affects the whole body) but…
DetailsAcne excoriee (AE) is a psychodermatosis which typically affects young women. It is a self-inflicted dermatosis which is admitted by the patients The patients pick on imagined papules and on physical examination, none of the elementary lesions of acne (comedones) are present. 2 types of psychological mechanisms explain the picking: habitual picking emotional picking Treatment…
DetailsCryotherapy is more effective when an appropriate technique is used. This depends on the specific effect (lien) one wishes to obtain, the shape of the lesion as well as the “strength” of the freezing. Open spray technique: method: directly spraying the lesion indication flat lesions (macular) examples: lentigos, actinic keratosis, superficial basal cell carcinoma, bowen’s…
DetailsAcne fulminans is the presence of very severe inflammatory acne lesions (nodules…) accompanied by systemic symptoms such as fever, joint pain. This is the most severe form of acne and requires the use of systemic steroids. Acne vulgaris is a common skin condition and can be mild, moderate or severe. Treatment is stepwise and starts…
DetailsCiclosporine works by calcineurin inhibition by intefering with T-lymphocyte transcription of IL-2. The long-term use of ciclosporine can be limited by the two major side effects of renal toxicity and hypertension. More recently it has been used in a short term approach via intermittent three- to four-month intervals, either to obtain a quick response before…
DetailsThe world is always changing (population ages, economies grow stronger or weaker), and healthcare systems adapt. In the United States since the economic crisis of 2008 the “Obama-care” health system arrived, bringing with it the advantages and disadvantages of a centralized government-controlled managed-care model. …Let’s talk about dermatology in Germany. Like Switzerland the healthcare system…
DetailsUstekinumab is a fully human monoclonal antibody against the common p40 subunit of IL-12 and IL-23. Two randomized, double-blind, placebo-controlled trials of ustekinumab have demonstrated significant and prolonged efficacy in the treatment of plaque psoriasis. Adverse events were generally similar across treatment and control groups. Studies are ongoing to assess the long term safety and…
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