The authors introduce the “DP-3 unifying concept”: acts on melanogenesis and melanosome transfer Study Formulation was applied twice daily in 33 women aged 31 to 68 Methods used and comments MASI: unreliable (Link) Physician global assessment (PGA) Photographic assessment: although it is claimed that a “significant depigmenting effect was demonstrated”, the pictures are not very…
An SPF (Sunprotection Factor) of 30 or more is recommended Physical sunscreens containing particles are privileged (over chemical sunscreens). Indeed physical sunscreens protect against all the visible light and not only UV rays. Sunprotection is only effective if sunexposure is avoided Contributors: Dr Christophe HSU – dermatologist. Geneva, Switzerland Source of Information: 2012 (09) –…
An SPF (Sunprotection Factor) of 30 or more is recommended Physical sunscreens containing particles are privileged (over chemical sunscreens). Indeed physical sunscreens protect against all the visible light and not only UV rays. Sunprotection is only effective if sunexposure is avoided Contributors: Dr Christophe HSU – dermatologist. Geneva, Switzerland Source of Information: 2012 (09) –…
The new generation (that is non-hydroquinone based) depigmentation creams also work… They are not as a group more effective than hydroquinone-based topicals(HQ)… …However they do have a much lower frequency and severity of side-effects Contributors: Dr Christophe HSU – dermatologist. Geneva, Switzerland Source of Information: 2012 (09) – Sachdev M. 21st Annual Congress of the…
Other articles deal with this issue however we can say here that lasers play a limited role: They are only indicated in the treatment of dermal melasma (chloasma, pregnancy mask). Even in this indication, the response is unpredictable* and the pigmentation tends to recur. Response to treatment has been reported for the following lasers (non-exhaustive…
Tranexamic acid is an antifibrinolytic which inhibits the conversion of plasminogen to plasmin. It has an antiallergic and antiinflammatory action. It might be effective in the treatment of melasma (chloasma, pregnancy mask): However tranexamic acid is in its inital stages and over the long run, the good results in the few reports* might not be…
Presented at the following Scientific Meeting: National Skin Centre (NSC) Dermatology Update, Singapore, 12-13 May 2012 Hsu.C. 1, Pourahmadi M.2, Ahmadi S. 2, Ali Mahdi H. 3. 1:Centre Medical du Lignon, Geneva, Switzerland. 2: Jahrom University Medical school, Jahrom, Iran. 3: Global Dermatology Information Portal. Royal Bahrain Hospital, Bahrain Introduction Cysteamine (mercaptoethylamine) is a product…
Melasma lesions show an increase in blood vessels (Chloasma, Pregnancy Mask) lesions when compared with perilesional skin (Kang HY 2010) Decrease in Melasma pigmentation with topical cream (triple combination cream with hydroquinone, a topical steroid and tretinoin) combined with PDL (Pulse-dye laser) (lien). Contributeurs Dr Christophe HSU – dermatologist. Geneva, Switzerland Source of Information: SY…
Melasma lesions show an increase in blood vessels (Chloasma, Pregnancy Mask) lesions when compared with perilesional skin (Kang HY 2010) Decrease in Melasma pigmentation with topical cream (triple combination cream with hydroquinone, a topical steroid and tretinoin) combined with PDL (Pulse-dye laser) (lien). Contributeurs Dr Christophe HSU – dermatologist. Geneva, Switzerland Source of Information: SY…
Recognizing melasma Melasma can be epidermal, dermal or mixed However, Wood’s light does no reliably define the depth of pigment Reflectance confocal microscopy is a more definitve method of doing so. Clinical Assesment of melasma is done through MASI (Melasma Area Severity Index) Melasma (Chloasma) (Pregnancy Mask): Differential Diagnosis: Post-inflammatory hyperpigmentation (PIH) Drug-induced (minocycline…) Frictional…
