Tranexamic acid is an antifibrinolytic which inhibits the conversion of plasminogen to plasmin. It has an antiallergic and antiinflammatory action. It might be effective in the treatment of melasma (chloasma, pregnancy mask): However tranexamic acid is in its inital stages and over the long run, the good results in the few reports* might not be…
Hydroquinone is the Gold Standard for treating Melasma (Chloasma, Pregnancy Mask). Numerous concentrations are used but a concentration of 4% in practice begins to be effective (and to have side-effects). Side effects include: erythema burning exogenous ochronosis confetti-like depigmentation In practice it is safe to use at 4% when closely supervised medically. Contributors: Dr Christophe…
Hydroquinone is the Gold Standard for treating Melasma (Chloasma, Pregnancy Mask). Numerous concentrations are used but a concentration of 4% in practice begins to be effective (and to have side-effects). Side effects include: erythema burning exogenous ochronosis confetti-like depigmentation In practice it is safe to use at 4% when closely supervised medically. Contributors: Dr Christophe…
In practice, when a patient is seen during a consultation, for a pigmentation problem, it is labelled “facial melanosis”. The most frequent cause of facial melanosis is chloasma (melasma, pregnancy mask) When in doubt should we do a biopsy on the face ? Yes, sometimes. Here are some other causes of facial melanosis: Leprosy when…
In practice, when a patient is seen during a consultation, for a pigmentation problem, it is labelled “facial melanosis”. The most frequent cause of facial melanosis is chloasma (melasma, pregnancy mask) When in doubt should we do a biopsy on the face ? Yes, sometimes. Here are some other causes of facial melanosis: Leprosy when…
Pigments There are two types of pigments (melanin) which determine skin colour in caucasians: Eumelanin: Has a photoprotective action Acts as a physical and chemical filter to light Absorbs free radicals in response to sun exposure Pheomelanin Is found most often in red-haired individuals Has a photoaggressive action Produces free radicals in response to sun…
Cysteamine cream as a new skin depigmenting product Hsu C.1, Ahmadi S.2, Pourahmad M.3, Ali Mahdi H.4,. 1 Centre Medical du Lignon Geneva, Switzerland 2, 3 : Jahrom Universty Medical school, Jahrom, Iran. 4: Global Dermatology Information Portal, Royal Bahrain Hospital, Bahrain Cysteamine hydrochloride (β-mercaptoethylamine hydrochloride) has been known to be a potent…
Topical isonicotinic acid hydrazide (isoniazid) as a new skin depigmenting compound Ahmadi S.1, Pourahmadi M.1, Aslani F.S.2, Kasraee B.3 1 Jahrom University of Medical Sciences, Jahrom, Iran 2 Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran 3 Scientis Pharma SA, Geneva, Switzerland Isonicotinic acid hydrazide (isoniazid) is the most commonly used antituberculosis medication. This…
Evaluation of a novel colorimetric technology for discrimination and measurement of cutaneous pigmentation and erythema Baquié Mathurin1, Kasraee Behrooz 2 1 Geneva, Switzerland 2 Scientis Pharma SA, Geneva, Switzerland Quantification of skin pigmentation by colorimeters is currently feasible. However, reproducibility and specificity of present devices is still limited. As a major inconvenience, alterations in skin…
Presented at the following Scientific Meeting: National Skin Centre (NSC) Dermatology Update, Singapore, 12-13 May 2012 Hsu.C. 1, Pourahmadi M.2, Ahmadi S. 2, Ali Mahdi H. 3. 1:Centre Medical du Lignon, Geneva, Switzerland. 2: Jahrom University Medical school, Jahrom, Iran. 3: Global Dermatology Information Portal. Royal Bahrain Hospital, Bahrain Introduction Cysteamine (mercaptoethylamine) is a product…
