-Polymorphous Light Eruption (PMLE): -appearance more papular in darker skin -PML patients are more resistant to UV-induced immunosuppression. Explains the “Hardening Concept”: desentisization treatment with UV light: enables immunotolerance -Voriconazole (antifungal): has been shown to induce developement of erythema, lentigenes, squamous cell carcinoma and melanoma –Vemurafenib (BRAF inhibitor used for the treatment of metastatic melanoma):…
A double blind randomized controlled trial on the safety and effectiveness of 10% Ipomoea muricata (Tonkin) ointment vs. mupirocin ointment for the treatment of localized primary bacterial skin infections Melanie Pauline G. Chao-Lo, Arnelfa C. Paliza, Daisy G. Cauilan, Jocelyn D. Domingo, Zennie B. Aceron Department of Dermatology, University of Santo Tomas Hospital, Philippines Background:…
Background: There has been an increasing incidence in the prevalence of adult acne vulgaris ranging between 30-50%. Androgens play a significant role in the pathogenesis of acne. Recently, hormonal therapy has been advocated as a first line therapy for acne vulgaris among female patients who experience premenstrual flares, acne beginning or worsening in adulthood and…
Poster: Treatment of Periocular Infantile Hemangiomas (Strawberry Nevi) with Topical Beta-Blockers INTRODUCTION Infantile hemangiomas (IH)(also called Strawberry Nevi) induce a higher risk of ocular amblyopia and the treatment by systemic beta blocking agents induces side-effects. The authors tried to evaluate the efficacy of timolol (a Beta-Blocker) applied topically. The authors did a retrospective study on…
Poster – Ertapenem in the Treatment of Severe Hidradenitis Suppurativa INTRODUCTION Verneuil’s disease is a poorly understood condition where the available treatments are quite often unsatisfactory. The authors demonstrate the efficacy of a large spectrum (also targets anaerobic germs) antibiotic called Etrapenem. The drug is administered intraveinously (central brachial catheter) at a dose of 1g/day…
Poster – The Role of Diet in Acne Vulgaris in Teenagers INTRODUCTION The role of diet in the development of acne vulgaris is still the object of controversy and the authors studied 1757 teenagers (aged 10 to 19) and after diagnosing acne clinically in some, they performed multiple data sampling and blood tests. Every time,…
Acne Vulgaris and Diet: Influence of the Environment History Until 1969, it was commonly admitted that dietary (and Behavioural) factors were implicated in the exacerbation of acne vulgaris. Such foods included chocolate, fats, sweets as well as sparkling soft drinks (such as Coca Cola). In 1969, a study on a small number of subjects concludes…
Nail Nevi and Melanoma -General Facts the lunula is part of the matrix and a melanocytic primary lesion implicates lunula involvement slow longitudinal thickening is a characteristic of melanoma (or at least it needs to be ruled out) -Signs that a lesion is not melanocytic arcuate white line associated with redness or pigmentation: in 98%…
Differential diagnosis of hypomelanoses in children (N. Van Geel (Ghent, Belgium)) Use a stepwise approach step 1 history congenital or acquired stable or progressive other medical problems family history step 2 clinical examination localisation (Woods light important especially in the localized form) number of lesions pattern (linear blaschkoid, segmental) hypomelanosis or amelanosis other problems (neurological, …
Pigmentary disorders of the skin during pregnancy (S. Vaughan Jones). melasma: types centrofacial malar mandbular histology epidermal (72% of cases) dermal (13%) Mixed in 5% occurs in 50-70% of pregnant women Hyperpigmentations: Mucosa (Vulval Melanosis), Areola, Axilla Linea Nigra Pigmentary Demarcation Lines (Voigt or Futcher’s lines) Darkening of Moles: there is a higher dermal proliferation…
