Basal Cell Carcinoma (BCC) is less common in the Asian population Pigmented variants are more common which suggests that PDT (Photodynamic Therapy) is not the most recommendable treatment for this population group The study concerned 45 patients with 95 lesions and included only those with phototypes IV and V: clearance rate at 4 months was…
Historical Events in the treatment of Hansen’s disease (Leprosy). 1943 – Paget reported promin treatment (sulphone) 1949 – dapsone introduced 1981 – MDT (Multi Drug Therapy) introduced 1964 – Dapsone resistance reported 1976 – Rifampicin resistance reported 2005 – Quinolone resistance reported 2007 – Cases of Resistance to MDT in 2007 reported 2009 – The…
Indications for PDT (Photodynamic Therapy) generally speaking include: Actinic Keratosis (AK): in Asian patients few studies are available One study enrolled 43 patients with 58 AK (located on the face) 85% cleared after 1 treatment at 4 weeks follow-up. Bowen’s disease (Squamous-Cell Carcinoma in situ): in a Singaporean study 43 patients were recruited lesions were…
Claw hand is the most common deformity in leprosy: It is due to paralysis of the intrinsic muscles hand which is innervated by the median and/or ulnar nerves. Leads to hyperextension of MCP (metacarophalangeal) joints and flexion of the IP (interphalangeal) joints. Management consists of occupational therapy and/or reconstruction surgery. In this case report from…
Actinic Keratosis (AK) in Japan: tend to be multiple 20% evolve into Squamous Cell Carcinoma (SCC) clinical types: macular, horn, papular, actinic cheilitis. All types can be pigmented: atypical keratinocytes containing melanin granules in the cytoplasm Aging of AK and histological caracteristics: early AKs: no parakeratosis atypical keratinocytes limited to the basal layer no budding…
Leprosy is a debilitating infectious disease prevalent in Brazil, India and Vietnam. The Authors sought to assess disabilities and impairment of quality of life in Ho Chi Minh City, Southern Vietnam. Study: 160 patients with leprosy induced disabilites answered a questionnaire WHO quality of life-BREFassessment questionnaire Results from the BREF questionnaire; scores: physical subdomain score …
Beware of skin colored tattooos (e.g around the mouth): Why ? There is high risk of pigment darkening upon removal (eg Q switched laser): thie pigment turns black (oxydation reaction) Solution: use COs laser ablation: superficial Beware of gold: Why ? if gold therapy was used for treatment of rhematoid arthririts, chrysiasis (deposit of…
Leprosy is not yet 100% eliminated but improving thanks to MDT (Multidrug Therapy)…but less and less aattention is devoted to it (only 25 attendees are present) Leprosy is part of the Neglected Tropical Diseases (NTD) according to the WTO http://www.who.int/neglected_diseases/diseases/en/) There are 3 in Indonesia when compared with Brazil The 3 NTD’s in Indonesia are…
Rare variant of lepromatous leprosy usually found in Mexico and Costa Rica. Also detected in Canada, Singapore, Brazil and Myanmar. Historical facts: described in 1852 by Lucio and Alvarado Etiology All described cases of Lucio’s phenomenon were caused by Mycobacterium lepromatosis which is more frequent in lepromatous leprosy and is the most common type of…
Known limitations: a reminder the result might might be good but “complete” hair removal is not possible ineffective on white hair Combining medical treatments with lasers Ornithin decarboxylaser (eflornithine) is a known treatment against hirsutism and is a known medical topical treatment to induce hair thinning. The presenter sought to evaluate the effect of…
