Oral therapy with Pycnogenol Derived from the French Maritime Pine (pinuspinaster) Trial done for 30 days in 30 women Tabs at a dosage of 25mg to take 3 times a day (daily dose = 75mg) Results show an improvement however no randomized control trials (RCT) have been done yet. Contributors: Dr Christophe HSU – dermatologist.…
Causes: resorcinol, phenol and mercury. Risk factors: olive or dark skin, failure to use sunprotection. Occurs with prolonged use of hydroquinone (HQ) at a concentration of more than 3%. FDA banned OTC (Over-the-counter) sale due to toxicology issues and uncertain long term cancer risk. However, it is considered safe when used at a concentration of…
Treatment of psoriasis is step by step: The base and most important is education and support Then comes topical treatment Then comes systemic treatment and/or phototherapy Does UVB (Ultraviolet type B) have a role to play in the treatment in psoriasis? US Survey on 387 dermatologists and asked what treatment they would use as first…
Evil is often depicted as scarring, balding and oculocutaneous albinisme. Goldfinger: The main mean character (Auric Goldfinger) has balding. You only Live Twice: The main mean character (Ernst Stavro Blofeld (Donald Pleasence)) has scarring as well as balding. He inspired Dr Evil in Austin Powers. The Man With The Golden Gun (Scaramanga (Christopher Lee): Has…
Skyfall: Raoul Silva (Javier Bardem) (the main mean character): no scars or tattoos as the villains usually have. However Bardem has a prosthetic jaw and when he takes it out, these are deformities in the skin Les Miserables: Anne Hathaway: very close-up there are closed comedones on forehead and cheeks: Adult Comedonal Acne Lincoln: Tommy…
Dahl A et al. Clinical Evaluation of the Efficacy and Tolerance of a product containing ellagic and salicylic acids in reducing hyperpigmentation and dark spots in comparison de 4% hydroquinone. The study included 54 females (30-65 years old, phototypes I to VI): they were randomly assigned to 2 groups application with either ellagic/salicylic acid or…
PDT: HOW DOES IT WORK ? PDT= photosensitizer + light + oxygen It was discovered in early 1900’s by a medical student (the professor claimed it first as his own !) Its action is through the generation of a singlet oxygen by using drugs and light. Porphyrin sensitizer* + light + porphyrin thus generates an…
Introduction PDT is commonly used in actininc keratosis (AK), basal cell carcinoma (BCC), squamous cell carcinoma (SCC), Bowen’s disease and acne vulgaris. The study enrolled 30 patients (5men, 25women) Metvix (methy-aminolelulinic acid) (Galderma) was applied 3 hours under occlusion before light application Aktilite 37J/cm2 (Galderma). 90 days after the procedure: the patients were clinically evaluated,…
American Academy of Dermatology (AAD) Meetings – USA European Academy of Dermatology and Venereology (EADV) Meetings – Europe European Society for Pediatric Dermatology (ESPD) Meetings – Europe European Society for Pigment Cell Research Meetings (ESPCR) – Europe Journées Dermatologiques de Paris (JDP) – France Regional Congress of Dermatology (RCD) Meetings – ASEAN Dermatological Society of…
They are indicated when conventionale treatment of itch has failed: refractory pruritus (chronic itch) Practical Attitude: identify the cause if there is one target the right type of itch Try many treatments, and stick to the one which works. Types of itch pruriceptive : skin neuropathic: central nervous system (CNS) and peripheral nervous (PNS) pathways…
