A few devices exist for the measurement of skin colour. These devices are generally called skin colorimeters. The most well-known existing colorimeters are Chromameter, Mexameter, and the newly developed device DermaCatch. Skin colorimeters are usually equipped with a handpiece which is put on the desired area of the skin and emits certain wavelenghts on the…
DetailsPrecise skin color (colour) measurement is of the utmost importance for researchers as well as clinicians involved in the field of skin pigmentation. Skin colorimetry has proved to be a delicate and rather complex issue. This complexity results from several facts: Skin erythema, which readily changes due to internal or external factors, can highly interfere…
DetailsIntroduction It is a skin disorder which concerns mainly Asians Clinically, Hori’s Nevus can coexist with melasma (chloasma, pregnancy mask) and or solar lentigos. It can be difficult to distinguish them*. *But it is important to distinguish them as Hori’s nevus responds well to the Nd-YAG 1064nm laser. However, solar lentigos (lentigenes) respond well to…
DetailsKojic acid It is a fungal metabolite which inhibits the enzyme tyrosinase. It binds to copper which becomes unusable by melanocytes. It is used at a concentration of 1% Its therapeutical effets are weak to moderate. Contributors: Dr Christophe HSU – dermatologist. Geneva, Switzerland Bibliography: Katsambas A. Melasma: Pathogenesis and Treatment. 70th Annual Meeting of…
DetailsKojic acid It is a fungal metabolite which inhibits the enzyme tyrosinase. It binds to copper which becomes unusable by melanocytes. It is used at a concentration of 1% Its therapeutical effets are weak to moderate. Contributors: Dr Christophe HSU – dermatologist. Geneva, Switzerland Bibliography: Katsambas A. Melasma: Pathogenesis and Treatment. 70th Annual Meeting of…
DetailsHydroquinone (HQ) Mechanism of action: hydroquinone inhibits activated tyrosinase activity (therefore it does not act on normal skin). A word on available concentrations: 2%: often ineffective 3-5%: good bleaching agent 6-10%: higher concentrations can cause irritation Side effects: Contact dermatitis (Both Allergic and Irritant) Nail Discoloration Exogenous Ochrnosis can rarely occur in dark skin individuals…
DetailsHydroquinone (HQ) Mechanism of action: hydroquinone inhibits activated tyrosinase activity (therefore it does not act on normal skin). A word on available concentrations: 2%: often ineffective 3-5%: good bleaching agent 6-10%: higher concentrations can cause irritation Side effects: Contact dermatitis (Both Allergic and Irritant) Nail Discoloration Exogenous Ochrnosis can rarely occur in dark skin individuals…
DetailsL-ascorbic acid (Vitamin C) Is an antioxidant Is used in the treatment of disorders of pigmentation including melasma (chloasma) (pregnancy mask) Alters the color of melanin from jet black to light tan Unstable as quickly oxidized Bibliography: Katsambas A (Conflicts of Interest: Abbott, Janssen-Cilag, Leo Pharma, Merck, Schering-Plough). Melasma: Pathogenesis and Treatment. 70e Réunion annuelle…
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