Cannabis to treat Acne ?

The authors sought to measure the effects of Cannabis sativa, (-)-cannabidiol (CBD) (a recreational drug) Results of the study show that: administration of CBD to cultured human sebocytes (cells that secrete sebum) and human skin organ culture inhibited the lipogenic actions of various compounds, including including testosterone. CBD suppresses sebocyte proliferation via the activation of…

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Mole checks and Melanoma detection

Strategies for early melanoma detection: Approaches to the patient with nevi. Goodson AG, Grossman D. J Am Acad Dermatol. 2009 May;60(5):719-35; quiz 736-8. doi: 10.1016/j.jaad.2008.10.065. Mole checks are the « bread and butter » of many dermatologists. The article summarizes the concepts of practical situations that arise when checking the skin or moles for melanoma: Should we…

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Melanoma: when to do a genetic screen in patients with a positive family history ?

Selection criteria for genetic assessment of patients with familial melanoma. Leachman SA, Carucci J, Kohlmann W, Banks KC, Asgari MM, Bergman W, Bianchi-Scarrà G, Brentnall T, Bressac-de Paillerets B, Bruno W, Curiel-Lewandrowski C, de Snoo FA, Debniak T, Demierre MF, Elder D, Goldstein AM, Grant-Kels J, Halpern AC, Ingvar C, Kefford RF, Lang J, MacKie…

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Photodynamic therapy is painful: any way around it ?

Pain associated with aminolevulinic acid-photodynamic therapy of skin disease. Warren CB, Karai LJ, Vidimos A, Maytin EV. J Am Acad Dermatol. 2009 Dec;61(6):1033-43. doi: 10.1016/j.jaad.2009.03.048. Photodynamic Therapy (or PDT) is a treatment involving the application of a photosensitizing substance (aminolevulinic acid (ALA), methyl-aminolevulinate MAL) for a few hours before shining a light for a few…

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Welcome to the Skin Planet !

The skin microbiome: current perspectives and future challenges. Chen YE, Tsao H. J Am Acad Dermatol. 2013 Jul;69(1):143-55. doi: 10.1016/j.jaad.2013.01.016. Different bacteria, fungi and viruses live on the skin. The type of microorganisms as well as their density depends on « environmental » factors. « Tropical » areas include the skin folds such as axillae, inquinal folds… ‘Desert » areas…

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Metastatic lung-cell cancer treatment with Erlotinib: its cutaneous side effects and practical management advice

Erlotinib-related skin toxicities: treatment strategies in patients with metastatic non-small cell lung cancer. Kiyohara Y, Yamazaki N, Kishi A. J Am Acad Dermatol. 2013 Sep;69(3):463-72. doi: 10.1016/j.jaad.2013.02.025. Targeted treatments against cancers have enhanced therapeutic properties as compared with older treatments. But with this also comes an array of new unwanted side-effects which are the results…

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