L-ascorbic acid (Vitamin C) Is an antioxidant Is used in the treatment of disorders of pigmentation including melasma (chloasma) (pregnancy mask) Alters the color of melanin from jet black to light tan Unstable as quickly oxidized Bibliography: Katsambas A (Conflicts of Interest: Abbott, Janssen-Cilag, Leo Pharma, Merck, Schering-Plough). Melasma: Pathogenesis and Treatment. 70e Réunion annuelle…
DetailsAcne vulgaris (pimples) (common acne) Actinic keratosis Contact allergy (Allergic contact dermatitis) Alopecia Areata Eczema and Atopic dermatitis Basal Cell Carcinoma (BCC) Photos Skin Signs of Internal Cancers Skin cancers Chicken Pox Skin Disorders in Young Children Chloasma (Melasma, Pregnancy Mask) Skin disorders induced by cosmetic products Darier’s Disease (Keratosis Follicularis) Dermatofibroma Diaper Candidiasis Skin…
DetailsNew Depigmenting substances: N-acetyl glucosamine Artocarpanone 4-n-butylresorcinol (rucinol) Ursolic Acid Anthraquinones Cinnamic Acid Macelignan Gallic Acid Glycine Isopanduratin A and 4-Hydroxypanduratin A Kurarinol, Kurarinidol and Trifolirhizin Pycnogenol 8% topical indomethacin cream Selina dien-8-one Taxifolin DeoxyArbutin and its second generation derivatives Hydroperoxy Traxastane t; type Triterpene Piceatannol Handog E. Brown Spots: Melasma Updates.2012 (02) – 20th…
DetailsNew Depigmenting substances: N-acetyl glucosamine Artocarpanone 4-n-butylresorcinol (rucinol) Ursolic Acid Anthraquinones Cinnamic Acid Macelignan Gallic Acid Glycine Isopanduratin A and 4-Hydroxypanduratin A Kurarinol, Kurarinidol and Trifolirhizin Pycnogenol 8% topical indomethacin cream Selina dien-8-one Taxifolin DeoxyArbutin and its second generation derivatives Hydroperoxy Traxastane t; type Triterpene Piceatannol Handog E. Brown Spots: Melasma Updates.2012 (02) – 20th…
DetailsThey act through: Tyrosinase Inhibition Inhibitors of Inflammation-induced Melanogenic Response Peroxidase inhibition Product Reduction and ROS (Radical Oxygen Scavengers) Tyrosinase inhibition hydroquinone 4-hydroxyanisole 4-S-CAP and derivatives Arbutin Aloesin Azelaic Acid Kojic Acid Ellagic Acid Resveratrol Oxyeresveratrol Licorice Extract Lactic Acid Inhibitors of Inflammation Induced Melanogenic Response Chamomille Corticosteroids Gliabridin Tranexamic Acid Peroxidase…
DetailsLichen Planus What is lichen planus ? It is an inflammatory condition of the skin. What is the chance of having it ? At any time, the frequency is evaluated at 0.5% of the population The development of lesions is triggered by stress. What does it look like ? It is characterized by violet bumps…
DetailsDr Christophe Hsu – dermatologist. Geneva, Switzerland How frequent is it ? It affects 1% of the population with a peak of 3-4 % in the 11 to 30 years old age group. Females are affected 3 times more than males. (controversial as some studies report no difference) How does it present ? It presents…
DetailsIn humans, melanin pigments are responsible for the visible color of the skin, hair and eyes. Although the blood within the dermis and exogenous pigments as carotenoids may play a role in producing different skin hues, variations in skin pigmentation between different ethnic groups (namely Negroid, Asian and Caucasians) is primarily determined by the amount…
Details4-OHA is a skin depigmenting agent with moderate efficacy and may be used for the treatment of hyperpigmentary disorders such as melasma and freckles. This agent decreases the number of melanin producing cells in the skin and can whiten the skin to a considerable degree. However, one should be aware of possible side effects such…
DetailsThe addition of 0.01% tretinoin to 4-OHA is shown by several studies to significantly enhance the skin depigmenting effect of 4-OHA. This combination is a very potent skin depigmenting formula and is used for the treatment of liver spots (senile lentigo). Liver spots are usually very resistant to depigmenting agents and are very hard to…
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