Low rates of clinical recurrence after biopsy of benign to moderately dysplastic melanocytic nevi (DN). Goodson AG, Florell SR, Boucher KM, Grossman D. J Am Acad Dermatol. 2010 Apr;62(4):591-6. Epub 2009 Dec 16. Clinical fear of melanoma leads to complete excision of dysplastic naevi (DN) when biopsy reveals postive margins. However this study opens the…
Study of the efficacy, tolerability, and safety of 2 fixed-dose combination gels in the management of acne vulgaris. Zouboulis CC, Fischer TC, Wohlrab J, Barnard J, Alió AB. Cutis. 2009 Oct;84(4):223-9. Combination creams for the treatment of moderate acne vulgaris are the new trend in therapeutic dermatology. The big issue of these products has been…
Ischemic colitis after mesotherapy combined with anti-obesity medications. Kim JB, Moon W, Park SJ, Park MI, Kim KJ, Lee JN, Kang SJ, Jang LL, Chang HK. World J Gastroenterol. 2010 Mar 28;16(12):1537-40. Mesotherapy as well as anti-obesity medications are advocated as the newest in body contouring and weight loss. While the latter is effective and…
Twice-daily versus once-daily applications of pimecrolimus cream 1% for the prevention of disease relapse in pediatric patients with atopic dermatitis. Ruer-Mulard M, Aberer W et al. Pediatr Dermatol. 2009 Sep-Oct;26(5):551-8. This article demonstrates that a once daily application of a calcineurin inhibitor (pimecrolimus in this stidy) is enough to prevent the flares of atopic dermatitis…
Effectiveness of Pulsed Dye Laser (PDL) in the Treatment of Recalcitrant Warts in Children. Sethuraman G, Richards KA, Hiremagalore RN, Wagner A Dermatol Surg 2009 Nov 13 This study lends evidence to the possibility of that PDL is a treatment option for recalcitrant warts in children. It achievs high cure rates as three quarters of…
Monitoring patients on methotrexate: hepatic fibrosis not seen in patients with normal serum assays of aminoterminal peptide of type III procollagen. Maurice PD, Maddox AJ, Green CA, Tatnall F, Schofield JK, Stott DJ. Br J Dermatol. 2005 Mar;152(3):451-8. Methotrexate therapy for conditions such as psoriasis are hepatotoxic. Regular monitoring of liver function is mandatory and…
Perioral abscess associated with isotretinoin. Beer K, Oakley H, Waibel J. J Drugs Dermatol. 2009 Nov;8(11):1034-6. “Watch out for patients developing infectious abscesses when on systemic isotretinoin treatment”. Patients on isotretinoin therapy have impaired skin and mucosal barrier function, thus rendering them more susceptible to infections. This case report highlights the need to suspect the…
