Diagnostic utility of dermatoscopy in hydroquinone-induced exogenous ochronosis. Mishra SN, Dhurat RS, Deshpande DJ, Nayak CS. Int J Dermatol. 2012 Feb 20. doi: 10.1111/j.1365-4632.2011.05305.x. Hydroquinone is a phenolic molecule given in various concentrations for the treatment of hyperpigmentary disorders such as melasma (chloasma) (pregnancy mask). It is also used as a whitening agent even though…
The effectiveness of anticellulite treatment using tripolar radiofrequency monitored by classic and high-frequency ultrasound. Mlosek RK, Woźniak W, Malinowska S, Lewandowski M, Nowicki A. J Eur Acad Dermatol Venereol. 2012 Jun;26(6):696-703. doi: 10.1111/j.1468-3083.2011.04148.x. Epub 2011 Jun 21. In this article, the authors propose a treatment which would be effective against cellulite. The treatment consists of…
Systemic therapy for primary hyperhidrosis: a retrospective study of 59 patients treated with glycopyrrolate or clonidine. Walling HW. J Am Acad Dermatol. 2012 Mar;66(3):387-92. Epub 2011 Aug 4. Hyperhidrosis is a socially bothersome and psychologically devastating condition which occurs spontaneously, but can reach extreme proportions in hot and humid wethaer conditions. Treatment options appear to…
Chloasma–the mask of pregnancy. Bolanca I, Bolanca Z, Kuna K, Vuković A, Tuckar N, Herman R, Grubisić G. Coll Antropol. 2008 Oct;32 Suppl 2:139-41. Review. Melasma (chloasma, pregnancy mask) can affect 50 to 70% of pregnant women and presents as symmetric hyperpigmented macules which can be located on cheeks, upper lip, chin, forehead The cause…
Preventing melasma recurrence: prescribing a maintenance regimen with an effective triple combination cream based on long-standing clinical severity. Arellano I, Cestari T, Ocampo-Candiani J, Azulay-Abulafia L, Bezerra Trindade Neto P, Hexsel D, Machado-Pinto J, Muñoz H, Rivitti-Machado MC, Sittart JA, Trindade de Almeida AR, Rego V, Paliargues F, Marques-Hassun K. J Eur Acad Dermatol Venereol.…
Importance of spironolactone in the treatment of acne in adult women. Saint-Jean M, Ballanger F, Nguyen JM, Khammari A, Dréno B. J Eur Acad Dermatol Venereol. 2011 Dec;25(12):1480-1. doi: 10.1111/j.1468-3083.2010.03926.x. Epub 2010 Nov 29. Acne Vulgaris is manageable with topical treatment and goes all the way to oral isotretinoin. However the later can have serious…
Kojic acid-induced IL-6 production in human keratinocytes plays a role in its anti-melanogenic activity in skin. Choi H, Kim K, Han J, Choi H, Jin SH, Lee EK, Shin DW, Lee TR, Lee AY, Noh M. J Dermatol Sci. 2012 Mar 14. Kojic acid is often used to treat various types of hyperpigmentation (ranging from…
Prospective cohort study on the effects and tolerability of flutamide in patients with female pattern hair loss. Paradisi R, Porcu E, Fabbri R, Seracchioli R, Battaglia C, Venturoli S. Ann Pharmacother. 2011 Apr;45(4):469-75. Epub 2011 Apr 12. For androgenetic alopecia, topical treatment is the mainstay and minoxidil is cumbersone to apply. Of all the combinations,…
Hydroquinone Therapy for Post-inflammatory Hyperpigmentation Secondary to Acne: Not Just Prescribable by Dermatologists. Chandra M, Levitt J, Pensabene CA. Acta Derm Venereol. 2011 Oct 17. doi: 10.2340/00015555-1225. In darker skin phototypes (Fitzpatrick IV and above), post inflammatory hyperpigmentation (PIH) following active inflammatory acne lesions (papules, pustules) is an issue and very common cause of emotional…
Improved survival with vemurafenib in melanoma with BRAF V600E mutation. Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, Dummer R, Garbe C, Testori A, Maio M, Hogg D, Lorigan P, Lebbe C, Jouary T, Schadendorf D, Ribas A, O’Day SJ, Sosman JA, Kirkwood JM, Eggermont AM, Dreno B, Nolop K, Li…
