Some of the infections which affect the body can manifest itself with some skin changes. This is what happens in Lyme disease (also called Borreliosis). Lyme disease is a bacterial illness caused by a spiral shaped bacteria (spirochete) named Borrelia burgdorferi. These are bacteria which are often found in deer. What happens is that the…
Lichen Planopilaris Treated With a Peroxisome Proliferator—Activated Receptor γ Agonist Paradi Mirmirani, MD and Pratima Karnik, PhD Arch Dermatol. 2009 December; 145(12): 1363–1366. Lichen planopilaris is a form of scarring alopecia and beyond dignosis and steroid treatment, little is available. This article shows an alternative therapeutic modality. The mode of action is through agnosit action…
If you are sensitive to sunlight, you may have a condition known as photosensitivity. Photosensitivity is often defined as the amount to which a person reacts upon receiving light. There are many conditions which can give rise to sensitivity of the skin to a light source. It is said that people with particular skin types…
Leprosy (Hansen’s disease) is an often ignored skin disease and this infectious disease can sometimes affect the nervous system. Non-specific nail changes can be found in Leprosy. The authors sought to study nail changes in leprosy: In this study cases of Hansen’s were collected from August 2011 to April 2012 (exclusion congenital nail deformities, fungal…
number of new cases in 2008: 17,441 number of new cases in 2012: 18,994 High number of new cases (CDR (case detection rate) more than 10 out of 10000 cases) in these Indonesian regions: Papua W Papua Maluku Sulawesi Java (as the population is a lot higher) Aceh (Sumatra) Subclinical leprosy is more…
PDT (Photodynamic therapy) acts through the elimination of the bacteria Propinibacterium Acnes Short contact with the photosensitizing substance is enough (less than 90 minutes vs around 4 hours for conventionnal indications) More effective for papulopustular lesions (vs comedonal) phototypes II and III carry a lower risk of (postinflammatory hyperpigmentation) PIH following treatment. The authors…
Leprosy is an infectious disease which affects the skin and the nerves. It is coming back mainly through imported cases…despite having being forgotten for a long time. It is prevalent in India and these common manifestations is why dermatology is taught together with leprosy (as it is with syphilis in many countries). In other words,…
Leprosy is a poorly understood infectious disease which leads to important discrimination. Although cases still occur Vietnam was met the WHO criteria for disease elimination in 2000. Out of the 87 million people living in Vietnam, there were 1336 cases reported in 2001; in 2012 this number fell to 296 cases. Leprosy in Vietnam –…
Basal Cell Carcinoma (BCC) is less common in the Asian population Pigmented variants are more common which suggests that PDT (Photodynamic Therapy) is not the most recommendable treatment for this population group The study concerned 45 patients with 95 lesions and included only those with phototypes IV and V: clearance rate at 4 months was…
Historical Events in the treatment of Hansen’s disease (Leprosy). 1943 – Paget reported promin treatment (sulphone) 1949 – dapsone introduced 1981 – MDT (Multi Drug Therapy) introduced 1964 – Dapsone resistance reported 1976 – Rifampicin resistance reported 2005 – Quinolone resistance reported 2007 – Cases of Resistance to MDT in 2007 reported 2009 – The…
