Atopic Dermatitis: a Short Summary
- PDT (Photodynamic therapy) acts through the elimination of the bacteria Propinibacterium Acnes
- Short contact with the photosensitizing substance is enough (less than 90 minutes vs around 4 hours for conventionnal indications)
- More effective for papulopustular lesions (vs comedonal)
- phototypes II and III carry a lower risk of (postinflammatory hyperpigmentation) PIH following treatment.
- The authors did a study:
- 13 patients divided into 2 groups:
- ALA (aminolevulinic acid) at a concentration of 20% in 6 patients
- 5% ALA in 7 patients
- The number of inflammatory papules was performed before and after the tratment:
- ALA 20%: the number of lesions dropped from 15 to 3
- ALA 5%: the number of lesions dropped from 18 to 7
- 13 patients divided into 2 groups:
Conclusion: ALA 5% is a suitable treatment option knowing that the advent of post-inflammatory hyperpigmentation was a lot lower than for ALA 20%.
Contributors
Dr Christophe Hsu – dermatologist. Geneva, Switzerland
Theng C. Photodynamic Therapy (PDT) in Asians. Photodermatosis and Ethnicity in Asian Skin. 2014 (4) – 21st Regional Conference of Dermatology; Danang (Vietnam)
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