Atopic Dermatitis: a Short Summary
- The study compares
- trichloroacetic acid (TCA): treatment applied every 2 weeks up to 8sessions
vs
- double frequency Q-switched Nd;YAG laser (1064nm and 532nm): treatment done once a month up to 6 sessions
Methods (and comments)
- 65 adult female patients were included
- Wood’s light to determine depth (sometimes unreliable)
- Evaluation through MASI: not reliable (Link)
- Follow up three months after the last treatment for recurrence
- Group 1
- epidermal location of the pigmentation
- n (number of patients) = 15, TCA 20%
- Group 2
- dermal and mixed (epidermal and dermal)
- n=20, TCA 25%
- Group 3
- dermal and mixed
- n=15, TCA 30%
- Group 4
- n=15:
- 7 with epidermal with wavelength at 532nm
- 8 dermal mixed location with wavelength at 1064nm
- n=15:
- Results show that the biggest improvement (64.7% +/- 21.9%) was seem in group 2 (TCA25%).
- The condition actaully worsened in group 4 (laser): (-49.2% +/- 66.3&)
- Recurrence rate was 32% siimilar in all 4 groups
- Conclusion and comment. Lasers actually worsened the melasma and this could be through the induction of post-inflammatory hyperpigmentation.
No conflicts of interest disclosed
Source of information: Alaa E. et al. P1422. Q-switched Nd:YAG laser versus trichloroacetic acid peeling in the treatment of melasma among Egyptian patients. European Academy of Dermatology and Venereology (EADV) Annual Meeting – Istanbul, Turkey, 2-6 October 2013
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