Oral Tranexemic Acid in the treatment of Melasma (Chloasma)(Pregnancy Mask): Efficacy Therapeutical effects of tranexamic acid have been shown in anecdotal reports Goh BK and al. treated 20 patients refractory to topical treatment with small doses of tranexamic acid (250mg twice a day) for 3 to 6 months. Assessment of results was done with photos,…
Oral Tranexemic Acid in the treatment of Melasma (Chloasma) (Pregnancy Mask): An Introduction Melasma (Chloasma) (Pregnancy Mask) is a frequent cause of acquired hyperpigmentation, particularly in Asian women. Although associated with sun exposure, pregnancy, oral contraceptives and hormones replacement therapy, the physiopathology of its development remains largely unknown. Locally applied agents (topicals) are the mainstay…
The role of blood vessels in melasma (chloasma) (pregnancy mask) Melasma (chloasma)(pregnancy mask) is characterized by hyperpigmented macules which also tend to appear in hyperestrogenic hormonal states. On histology, there is an increased deposit of melanin in the epidermis. Clinically, melasma lesions are also characterized by redness and telangiectasia. This equates to an increased number…
Prospective new biologic therapies for psoriasis and psoriatic arthritis. Mortel MR, Emer J. J Drugs Dermatol. 2010 Aug;9(8):947-58. In the very young and trendy world of the “biologics” in the treatment arsenal of Psoriasis and Psoriastic arthritis, agents with different molecular targets have come. Some like Etanercept and Infliximab are thriving and some because of…
