Dr Christophe HSU – dermatologist. Geneva, Switzerland Pruritus It may appear up to 2 years before the onset of cirrhosis 40% of alcohol abusers with liver disease are estimated to have severe pruritus generalized but with predilection to extensor extremities, upper trunk, palms and soles chemical mediators (Bile acids) are thought to directly depolarize nerve…
DetailsJaundice due to the deposition of billirubin, product of the breakdown of heme: accumulation in the liver due to impaired hepatic conjugation. It subsequently binds tissues with a special affinity to elastin. detectable with serum levels above 2.5 mg/dL The ocular sclera are often the first to turn yellow. Differential Diagnosis (DD): prehepatic, hepatic (Primary…
DetailsPancreatitis Due to alcohol abuse in 65% of cases Clinically: Panniculitis also called nodular cystosteatonecrosis or cutaneous nodular adiponecrosis: mechanism thought to be due to the liberation of enzymes in the circulation directly or through lymphatic channels found in the male between 40 and 70 years old clinically: dermohypodermic inflammatory plaques predominantly located in the…
DetailsDr Christophe Hsu – dermatologist. Geneva, Switzerland Urticarial and anaphylactoid reactions reported to occur minutes after alcohol intake. May occur with anaphylactic symptoms reproductible with oral challenge with ethyl alcohol (=ethanol). may have genetic intolerance with defects in alcohol-metabolizing enzymes (Oriental flushing syndromes). Many though develop a reaction after red or white wine intake suggesting…
DetailsMalnutrition Zinc Clinically: erythematous crusting erosive sometimes bullous dermatitis periorificial: buccal, nasal, palpebral, anal, vulval, genital, flexural progressive alopecia diagnosis and treatment: reduced blood Zn and alkaline phosphatase, sometimes also reduced non esterified essential fatty acids (linoleic and arachidonic acid). IV or oral by zinc salts (gluconate, sulfate) leads to spectacular cures. Essential Fatty Acids…
DetailsInfections: as the associations are incompletely understood, we have selected and summarized an article in the scientific literature Ness KJ, Fan J, Wilke WW, Coleman RA, Cook RT, Schlueter AJ. Chronic ethanol consumption decreases murine Langerhans cell numbers and delays migration of Langerhans cells as well as dermal dendritic cells. Alcohol Clin Exp Res. 2008…
DetailsSkin Aging: due to the partial understanding of the association, we have selected the following article from the scientific literature. Von Wurmb-Schwark N, Ringleb A, Schwark T, Broese T, Weirich S, Schlaefke D, Wegener R, Oehmichen M. The effect of chronic alcohol consumption on mitochondrial DNA mutagenesis in human blood. Mutat Res. 2008 Jan 1;637(1-2):73-9.…
DetailsAlcohol (OH) and the Skin – Table of Contents Skin Cancer by immunosuppression by associated nutritional deficiencies which alter mucosal integrity by impairing detoxification promotion: eg ENT Scc, oral for BCC incidence increased as well as infiltrative behaviour unclear for malignant melanoma. Due to the incomplete understanding as of today of the association, we have…
DetailsAlexiTriVantage ® GentleLase ® GentleMax ® GentleYAG ® QuadraLase ® Smoothbeam ® VBeam ® Note that the list is updated regularly as all companies and products are not included. This is simply a guide to devices which are known to the authors of the website. Full-indications may not be included and side effects are not…
DetailsRevlite ® Medlite ® C-series V-Raser ® DermaSculpt ® Note that the list is updated regularly as all companies and products are not included. This is simply a guide to devices which are known to the authors of the website. Full-indications may not be included and side effects are not mentioned. All the content may…
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