What is photodynamic therapy (PDT) ? It is a technique which consists of producing activated oxygen by using a photsensitizing substance combined with a source of light. How does it work ? Applying a cream (containing aminolevulinic acid) enables it to combine with porphyrins. The latter then become activated thus susceptible to light. Their reaction…
Evil is often depicted as scarring, balding and oculocutaneous albinisme. Goldfinger: The main mean character (Auric Goldfinger) has balding. You only Live Twice: The main mean character (Ernst Stavro Blofeld (Donald Pleasence)) has scarring as well as balding. He inspired Dr Evil in Austin Powers. The Man With The Golden Gun (Scaramanga (Christopher Lee): Has…
Skyfall: Raoul Silva (Javier Bardem) (the main mean character): no scars or tattoos as the villains usually have. However Bardem has a prosthetic jaw and when he takes it out, these are deformities in the skin Les Miserables: Anne Hathaway: very close-up there are closed comedones on forehead and cheeks: Adult Comedonal Acne Lincoln: Tommy…
Dahl A et al. Clinical Evaluation of the Efficacy and Tolerance of a product containing ellagic and salicylic acids in reducing hyperpigmentation and dark spots in comparison de 4% hydroquinone. The study included 54 females (30-65 years old, phototypes I to VI): they were randomly assigned to 2 groups application with either ellagic/salicylic acid or…
PDT: HOW DOES IT WORK ? PDT= photosensitizer + light + oxygen It was discovered in early 1900’s by a medical student (the professor claimed it first as his own !) Its action is through the generation of a singlet oxygen by using drugs and light. Porphyrin sensitizer* + light + porphyrin thus generates an…
Introduction PDT is commonly used in actininc keratosis (AK), basal cell carcinoma (BCC), squamous cell carcinoma (SCC), Bowen’s disease and acne vulgaris. The study enrolled 30 patients (5men, 25women) Metvix (methy-aminolelulinic acid) (Galderma) was applied 3 hours under occlusion before light application Aktilite 37J/cm2 (Galderma). 90 days after the procedure: the patients were clinically evaluated,…
American Academy of Dermatology (AAD) Meetings – USA European Academy of Dermatology and Venereology (EADV) Meetings – Europe European Society for Pediatric Dermatology (ESPD) Meetings – Europe European Society for Pigment Cell Research Meetings (ESPCR) – Europe Journées Dermatologiques de Paris (JDP) – France Regional Congress of Dermatology (RCD) Meetings – ASEAN Dermatological Society of…
Dermatomyositis is is a type of inflammatory disease characterized by muscle weakness and a distinctive skin rash. Epidemiology Dermatomyositis is a condition which affects both adults and children. In adults, dermatomyositis usually occurs from the late 40s to early 60s, while in children, the disease most often appears between 5 and 15 years of age.…
They are indicated when conventionale treatment of itch has failed: refractory pruritus (chronic itch) Practical Attitude: identify the cause if there is one target the right type of itch Try many treatments, and stick to the one which works. Types of itch pruriceptive : skin neuropathic: central nervous system (CNS) and peripheral nervous (PNS) pathways…
Dr Christophe Hsu – dermatologist. Geneva, Switzerland What is Darier’s disease (keratosis follicularis) ? Also called Darier-White Disease. Is one of the most common genodermatosis and affects one person out of 30000. It is inherited in an autosomal dominant pattern. What is it caused by ? The mutated gene codes for a calcium channel regulator.…
