Capsaicin used topically is used in the treatment of pain following for example shingles = post herpetic neuralgia. In the following study, capsaicin receptors appear to be reduced Capsaicin receptor is also known as TRPV1 32 Patients with psoriasis (lesional) were compared with 20 with normal skin Results TRPV1 was found by RTPCR (polymerase chain…
Pathogenesis of melasma (chloasma) (pregnancy mask) remains unknown. Treatment which is effective on the epidermal component of the pigmentation acts by the following mechnisms: inhibition of melanin synthesis blockage of melanosome transker from melanocytes and keratinocytes (niacinamide). Solar eviction and photoprotection are a crucial element in the treatments. The gold standard in the treatment of…
Acupuncture is known as a treatment of chronic symptoms such as pain, joint pain and the like and the following study shows interesting results in the treatment of itch (pruritus). In this in vivo study, *90 mice were treated: with a substance substance causing itch (in 30 mice) (compound 48/80) (subcutaneous injection behind the…
Hydroquinone is the gold standard in the treatment of hyperpigmentary disorders but there are 3. things to bear in mind: -a concentration of 4% or more is needed to be effective. -because of a higher concecntration, side effects such as exogenous ochronosis are a risk. Because of a lack of evidence pertaining to long term…
