L’alcool et la peau (éthylisme) – Table des matières
Skin Aging: due to the partial understanding of the association, we have selected the following article from the scientific literature.
- Von Wurmb-Schwark N, Ringleb A, Schwark T, Broese T, Weirich S, Schlaefke D, Wegener R, Oehmichen M. The effect of chronic alcohol consumption on mitochondrial DNA mutagenesis in human blood. Mutat Res. 2008 Jan 1;637(1-2):73-9. Epub 2007 Jul 21.
- The 4977bp deletion of mitochondrial DNA (mtDNA) is known to accumulate with increasing age in post mitotic tissues.
- Authors investigated mitochondrial mutagenesis in 69 patients with a chronic alcoholic disease and 46 age matched controls with a moderate drinking behavior.
- The relative amount of 4977bp deleted mtDNA in alcoholics was significantly increased compared to controls.
- The results suggest that mtDNA mutagenesis in blood can be influenced by stressors such as alcohol. Ethanol seems to be a significant factor to alter mitochondrial DNA in blood and might be an additional contributor for the cellular aging process.
Related posts