Mesothelioma is one of the most severe cancers which develops from the mesothelial lining which wraps some organs: the lungs (more precisely the pleura) the heart (pericardium) the abdominal cavity (peritoneum) the testicles (tunica vaginalis)… It is an occupational related condition (for the lungs) due to the exposure to asbestos (and erionite). Although there is…
Mesothelioma can initially be Diagnosed on Skin Lesions: Malignant mesothelioma presenting as a lip tumor: report of two cases with one unrecognized by 166 pathologists. Beer TW, Heenan PJ. Am J Dermatopathol. 2007 Aug;29(4):388-91. Cutaneous metastases as the first manifestation of pleural malignant mesothelioma. Maiorana A, Giusti F, Cesinaro AM, Conti A, Rossi G. J…
Mesothelioma can extend to the skin Directly (contiguous spread) Developing as skin nodules on scars (surgical or not) Peritoneal mesothelioma presenting as a skin nodule. Abban C, Viglione M. J Cutan Pathol. 2009 Jun;36(6):675-9. Benign multicystic peritoneal mesothelioma in a cesarean-section scar presenting as a fungating mass. Cuartas JE, Maheshwari AV, Qadir R, Cooper AJ,…
Diagnosis and treatment of mesothelioma can induce changes on the skin Acute generalized exanthematic pustulosis (AGEP) after Pemextred (folate antagonist) use Acute generalized exanthematous pustulosis after pemetrexed, and recurrence after re-introduction. Bracke A, Van Marck E, Lambert J. Clin Exp Dermatol. 2009 Apr;34(3):337-9. Epub 2008 Aug 9. Erysipeloid skin lesions Gemcitabine-induced erysipeloid skin lesions in…
Mesothelioma could induce skin lesions: Antiphospholid Syndrome Mesothelioma-associated antiphospholipid antibody syndrome presenting with cutaneous infarction and neuropathy. Tucker SC, Coulson IH, Salman W, Kendra JR, Johnson CE. Br J Dermatol. 1998 Jun;138(6):1092-4. Epitheloid Granulomatous reaction [Generalized epithelioid granulomatous reaction with myeloproliferative syndrome associated with pleural mesothelioma and Kaposi’s sarcoma]. Peychl L, Dorazilová V. Cesk Patol.…
