Acne fulminans is the presence of very severe inflammatory acne lesions (nodules…) accompanied by systemic symptoms such as fever, joint pain. This is the most severe form of acne and requires the use of systemic steroids. Acne vulgaris is a common skin condition and can be mild, moderate or severe. Treatment is stepwise and starts…
Ciclosporine works by calcineurin inhibition by intefering with T-lymphocyte transcription of IL-2. The long-term use of ciclosporine can be limited by the two major side effects of renal toxicity and hypertension. More recently it has been used in a short term approach via intermittent three- to four-month intervals, either to obtain a quick response before…
The world is always changing (population ages, economies grow stronger or weaker), and healthcare systems adapt. In the United States since the economic crisis of 2008 the “Obama-care” health system arrived, bringing with it the advantages and disadvantages of a centralized government-controlled managed-care model. …Let’s talk about dermatology in Germany. Like Switzerland the healthcare system…
Ustekinumab is a fully human monoclonal antibody against the common p40 subunit of IL-12 and IL-23. Two randomized, double-blind, placebo-controlled trials of ustekinumab have demonstrated significant and prolonged efficacy in the treatment of plaque psoriasis. Adverse events were generally similar across treatment and control groups. Studies are ongoing to assess the long term safety and…
When getting a new patient, it is often secondary to recommendation by patients in their network. It’s the same for social media except that it is not word-of-mouth but word of mouth on steroids. Here is an example of rating sites which include doctors in the United States: Yelp Healthgrades Vitals Zocdoc Webmd Doctors…
Milestones in invention of e-technologies 1971 – Email 1985 – AOL 1993 – www (internet) 1998 – Google 2001 – Wikipedia 2004 – Facebook 2005 – Youtube 2006 – Twitter 2007 – Iphone 2010 – Ipad All technologies have evolved and they are being used with different frequencies – for example today emails are used…
How does cryosurgery/cryotherapy work ? Cryotherapy acts by taking the heat out of tissues. To take the heat out conduction of heat is important: it is highest for metals ( for example with probes), then ice (for example freezing just after having done it once), then water (by wetting the lesion to be treated and…
Rosacea is a common dermatological condition affecting 0,5 – 1 % of the population which represents over 15 million individuals in the United States It is sometimes classified in stages 1 (erythema and telangiectasia), 2 and 3 (rhinophyma). It is an important cause of distress and social withdrawal. Around 60% of individuals with stage 1…
In deciding which therapy to use, many factors must be taken into consideration, including safety, efficacy, availability, and cost. Long-term side effects will, of course, become better known as experience with each therapy grows. In particular, biologic medications are already in their second decade of use in rheumatology, but there is much less experience than…
Rosacea is still a mystery with regards to etiology but it has been suggested that the Demodex mite might be associated with its presence and/or severity. Canthelicidines are antimicrobial peptides that protect the skin through: direct antimicrobial activity by initiating a hosp response resulting in cytokine release, inflammation, angiogenesis and reepitheliazation. In rosacea the…
