Posts Tagged ‘Trouver des nouveaux agents dépigmentants: comprendre les voies de régulation pour conceptualiser des nouveaux traitements’
Understanding the Pathways Regulating the Production of Melanin to Conceptualize New Treatments (For Professionals)
Sunday, May 12th, 2013The authors constructed the molecular regulatory network of melanogenesis by focusing on 2 pathways: paracrine factor-mediated signaling pathway Microphthalmia-associated transcription factor-related pathway By reviewing the literature, the authors established a “Boolean network model” that describes the dynamical characteristics of the network: Molecules which would decrease pigmentation: CREB, MITF protein, MITF active, GSK3B, CAMP, AC, PKA, […]
