Posts Tagged ‘Griscelli Syndrome’
Synthesis of Melanin and its Disturbances
Sunday, May 13th, 2012Melanin is produced by mature melanocytes. The biosynthesis of melanin is a complex which implicateds numerous enzymes which include tyrosinase, TRP1, TRP2…Genetic disturbances of these enzymes can result in a pigmentary dilution which translates clinically with depigmentation as is seen for example in oculocutaneous albinism. The production of melanin is done within melanocytes in organelles […]