Mesothelioma and the Skin: Diagnostic and Therapeutical Creation of of Skin Lesions (For Professionals)

Diagnosis and treatment of mesothelioma can induce changes on the skin

• Acute generalized exanthematic pustulosis (AGEP) after Pemextred (folate antagonist) use

Acute generalized exanthematous pustulosis after pemetrexed, and recurrence after re-introduction.

Bracke A, Van Marck E, Lambert J.

Clin Exp Dermatol. 2009 Apr;34(3):337-9. Epub 2008 Aug 9.

• Erysipeloid skin lesions

Gemcitabine-induced erysipeloid skin lesions in a patient with malignant mesothelioma.

Kuku I, Kaya E, Sevinc A, Aydogdu I.

J Eur Acad Dermatol Venereol. 2002 May;16(3):271-2

• Radiation recall dermatitis

Radiation recall dermatitis with pemetrexed.

Hureaux J, Le Guen Y, Tuchais C, Savary L, Urban T.

Lung Cancer. 2005 Nov;50(2):255-8. Epub 2005 Aug 18.

Hemithoracic radiation after extrapleural pneumonectomy for malignant pleural mesothelioma.

Yajnik S, Rosenzweig KE, Mychalczak B, Krug L, Flores R, Hong L, Rusch VW.

Int J Radiat Oncol Biol Phys. 2003 Aug 1;56(5):1319-26.

• Subcutaneous Seeding

Subcutaneous seeding after ultrasound-guided placement of intrapleural catheter. An unusual complication of the intracavitary palliative treatment of pleural mesothelioma.

Sartori S, Nielsen I, Trevisani L, Tassinari D, Abbasciano V.

Support Care Cancer. 1999 Sep;7(5):362-4.

Subcutaneous tumor growth complicating the positioning of Denver shunt and intrapleural port-à-cath in mesothelioma patients.

van Ooijen B, Eggermont AM, Wiggers T.

Eur J Surg Oncol. 1992 Dec;18(6):638-40.

[Metastatic seeding by pleural biopsy].

Blanchette G, Maunier N, Provost G.

Union Med Can. 1973 Feb;102(2):330-4. French.