Mesothelioma and the Skin: Metastases (For Professionnals)

Mesothelioma can extend to the skin

• Directly (contiguous spread)

• Developing as skin nodules on scars (surgical or not)

Peritoneal mesothelioma presenting as a skin nodule.

Abban C, Viglione M.

J Cutan Pathol. 2009 Jun;36(6):675-9.

Benign multicystic peritoneal mesothelioma in a cesarean-section scar presenting as a fungating mass.

Cuartas JE, Maheshwari AV, Qadir R, Cooper AJ, Robinson PG, Pitcher JD Jr.

Int J Clin Oncol. 2008 Jun;13(3):275-8. Epub 2008 Jun 14.

Pleural mesothelioma with cutaneous extension to chest wall scars.

Shieh S, Grassi M, Schwarz JK, Cheney RT.

J Cutan Pathol. 2004 Aug;31(7):497-501.

• By developing on normal skin

[Cutaneous metastasis of pleural mesothelioma: two cases].

Gaudy-Marqueste C, Dales JP, Collet-Villette AM, Grob JJ, Astoul P, Richard MA.

Ann Dermatol Venereol. 2003 Apr;130(4):455-9. French.

[Latero-thoracic cutaneous metastases of an underlying pleural cancer].

Michel PJ, Vanstraaten L, Cretin J, Cassin B.

Bull Soc Fr Dermatol Syphiligr. 1966 Sep-Nov;73(5):543-4. French.

• Indirectly (hematogenous or lymphatic spread)

Skin metastasis of pleural epithelioid malignant mesothelioma.

Terada T.

Appl Immunohistochem Mol Morphol. 2011 Jan;19(1):92-3.

Late cutaneous metastases to the face from malignant pleural mesothelioma: a case report and review of the literature.

Elbahaie AM, Kamel DE, Lawrence J, Davidson NG.

World J Surg Oncol. 2009 Nov 9;7:84. Review.

Disseminated cutaneous metastasis of a biphasic pleural mesothelioma.

Müller CS, Reichrath J, Tilgen W.

J Eur Acad Dermatol Venereol. 2009 Feb;23(2):226-7. Epub 2008 Jun 6.

Malignant pleural mesothelioma with scalp, cerebellar, and finger metastases: a rare case.

Kanbay A, Oguzulgen KI, Ozturk C, Memis L, Demircan S, Kurkcuoglu C, Akyurek N, Kurul C.

South Med J. 2007 Jan;100(1):63-5.

Subcutaneous metastasis of peritoneal mesothelioma diagnosed by fine-needle aspiration.

Pappa L, Machera M, Tsanou E, Damala C, Peschos D, Bafa M, Malamou-Mitsi V.

Pathol Oncol Res. 2006;12(4):247-50. Epub 2006 Dec 25.

Subcutaneous metastases of sarcomatoid mesothelioma with its differential diagnosis on fine needle aspiration–a case report.

Patel T, Bansal R, Trivedi P, Modi L, Shah MJ.

Indian J Pathol Microbiol. 2005 Oct;48(4):482-4.

[Cutaneous metastasis of the pleural mesothelioma].

Bachmeyer C, Reynaert G, Le Lann P, Cazier A, Lamarque G.

Ann Dermatol Venereol. 2004 Mar;131(3):287-8. French.

Widespread cutaneous and perioral metastases of mesothelioma.

Cassarino DS, Xue W, Shannon KJ.

J Cutan Pathol. 2003 Oct;30(9):582-5.

Tongue metastasis from a malignant diffuse mesothelioma of the pleura: report of a case.

Piattelli A, Fioroni M, Rubini C.

J Oral Maxillofac Surg. 1999 Jul;57(7):861-3.

Distant cutaneous metastasis of pleural malignant mesothelioma.

Dutt PL, Baxter JW, O’Malley FP, Glick AD, Page DL.

J Cutan Pathol. 1992 Dec;19(6):490-5.

Peritoneal malignant mesothelioma with multiple distant skin metastases.

Ordóñez NG, Smith JL Jr.

Arch Dermatol. 1983 Oct;119(10):827-30.

[Cutaneous dissemination, after biopsy, of a pleural mesothelioma observed in Dakar].

Monnier A, Derrien JP, Lartisien D, Diop L, Varieras G, Thomas J.

Bull Soc Med Afr Noire Lang Fr. 1977;22(2):191-3. French.

[Scalp metastases of pleural mesothelioma].

Bazex A, Miguères J, Dupré A, Christol B, Jover A, Cantala P.

Bull Soc Fr Dermatol Syphiligr. 1969;76(1):99-101. French.