Cholesterol and the Skin (Hypercholesterolemia) – Skin conditions induced by statin use (treatment)(for professionals)

Skin conditions associated with statin (cholesterol lowering drug) (HMG-CoA reductase inhibitors) use:

• chronic urticaria
• contact dermatitis
• dermatomyositis
• erythema multiforme
• ichtyosis (not specified)
• lichen planus-like reactions, lichen planus pemphigoides
• lichenoid drug eruption
• linear Iga bullous dermatosis
• polymyositis
• subacute lupus erythematosus
• systemic lupus erythematosus

Bibliography

Chronic urticaria to atorvastatin. Anliker MD, Wüthrich B. Allergy. 2002 Apr;57(4):366.

Erythema multiforme photoinduced by statins. Rodríguez-Pazos L, Sánchez-Aguilar D, Rodríguez-Granados MT, Pereiro-Ferreirós MM, Toribio J. Photodermatol Photoimmunol Photomed. 2010 Aug;26(4):216-8.

Ichthyosis induced by cholesterol-lowering drugs. Implications for epidermal cholesterol homeostasis. Williams ML, Feingold KR, Grubauer G, Elias PM. Arch Dermatol. 1987 Nov;123(11):1535-8.

Linear IgA bullous dermatosis induced by atorvastatin. König C, Eickert A, Scharfetter-Kochanek K, Krieg T, Hunzelmann N. J Am Acad Dermatol. 2001 Apr;44(4):689-92.

Lupus erythematosus and other autoimmune diseases related to statin therapy: a systematic review. Noël B. J Eur Acad Dermatol Venereol. 2007 Jan;21(1):17-24.

Pravastatin-induced lichenoid drug eruption. Pua VS, Scolyer RA, Barnetson RS. Australas J Dermatol. 2006 Feb;47(1):57-9.

Simvastatin – occupational contact dermatitis. Field S, Bourke B, Hazelwood E, Bourke JF. Contact Dermatitis. 2007 Oct;57(4):282-3.