Specialized Subjects in Dermatology
Menu Specialized Subjects in Dermatology
Alcohol (OH) and the Skin – Jaundice (Icterus) (For professionals)
Saturday, July 24th, 2010Jaundice due to the deposition of billirubin, product of the breakdown of heme: accumulation in the liver due to impaired hepatic conjugation. It subsequently binds tissues with a special affinity to elastin. detectable with serum levels above 2.5 mg/dL The ocular sclera are often the first to turn yellow. Differential Diagnosis (DD): prehepatic, hepatic (Primary […]
Alcohol (OH) and the Skin – Pancreatitis (For professionals)
Friday, July 23rd, 2010Pancreatitis Due to alcohol abuse in 65% of cases Clinically: Panniculitis also called nodular cystosteatonecrosis or cutaneous nodular adiponecrosis: mechanism thought to be due to the liberation of enzymes in the circulation directly or through lymphatic channels found in the male between 40 and 70 years old clinically: dermohypodermic inflammatory plaques predominantly located in the […]
Alcohol (OH) and the Skin – Urticaria and Anaphylactoid reactions (For professionals)
Thursday, July 22nd, 2010Dr Christophe Hsu – dermatologist. Geneva, Switzerland Urticarial and anaphylactoid reactions reported to occur minutes after alcohol intake. May occur with anaphylactic symptoms reproductible with oral challenge with ethyl alcohol (=ethanol). may have genetic intolerance with defects in alcohol-metabolizing enzymes (Oriental flushing syndromes). Many though develop a reaction after red or white wine intake suggesting […]
Alcohol (OH) and the Skin – Malnutrition (For professionals)
Wednesday, July 21st, 2010Malnutrition Zinc Clinically: erythematous crusting erosive sometimes bullous dermatitis periorificial: buccal, nasal, palpebral, anal, vulval, genital, flexural progressive alopecia diagnosis and treatment: reduced blood Zn and alkaline phosphatase, sometimes also reduced non esterified essential fatty acids (linoleic and arachidonic acid). IV or oral by zinc salts (gluconate, sulfate) leads to spectacular cures. Essential Fatty Acids […]
Alcohol (OH) and the Skin – Infections (For professionals)
Tuesday, July 20th, 2010Infections: as the associations are incompletely understood, we have selected and summarized an article in the scientific literature Ness KJ, Fan J, Wilke WW, Coleman RA, Cook RT, Schlueter AJ. Chronic ethanol consumption decreases murine Langerhans cell numbers and delays migration of Langerhans cells as well as dermal dendritic cells. Alcohol Clin Exp Res. 2008 […]
Alcohol (OH) and the Skin – Skin Aging (For professionals)
Monday, July 19th, 2010Skin Aging: due to the partial understanding of the association, we have selected the following article from the scientific literature. Von Wurmb-Schwark N, Ringleb A, Schwark T, Broese T, Weirich S, Schlaefke D, Wegener R, Oehmichen M. The effect of chronic alcohol consumption on mitochondrial DNA mutagenesis in human blood. Mutat Res. 2008 Jan 1;637(1-2):73-9. […]
Alcohol (OH) and the Skin – Skin Cancer (For professionals)
Sunday, July 18th, 2010Alcohol (OH) and the Skin – Table of Contents Skin Cancer by immunosuppression by associated nutritional deficiencies which alter mucosal integrity by impairing detoxification promotion: eg ENT Scc, oral for BCC incidence increased as well as infiltrative behaviour unclear for malignant melanoma. Due to the incomplete understanding as of today of the association, we have […]
Hansen’s Disease (Leprosy) – Treatment (For professionals)
Friday, June 11th, 2010I. Anti-leprosy treatments Modern treatment for leprosy was introduced in 1941 when dapsone and its derivatives were used. Prior to that, the segregation of patients in a leprosarium by law was intended to prevent the spread of leprosy to the community. With effective chemotherapy, leprosy is curable today and treatment is undertaken by the general […]
Hansen’ Disease (Leprosy) – Complications (For Professionals)
Thursday, June 10th, 2010The importance of leprosy lies in its ability to cause permanent disabilities from damage to nerves and eyes. Nerve damage can be due to granulomatous lesions that result in fibrosis, during reactions when severe inflammation results in nerve destruction and from ischaemia caused by pressure on the vasa nervosa. . The residual nerve deficit that […]
Hansen’s Disease (Leprosy) – Diagnostic tests (For professionals)
Thursday, June 10th, 2010Histological examination of the skin lesion and nerve for the typical histological changes and the presence of acid-fast bacilli is required for the definitive diagnosis of leprosy. All cases of leprosy should preferably be confirmed histologically as labeling a person with leprosy carries with it dire social and medical implications. Slit skin smear to detect […]
