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©Viagra (Sildenafil) in the treatment of Raynaud’s phenomenon
Saturday, December 14th, 2013Sildenafil which is more commonly known by its brand name ©Viagra is a phosphodiesterase inhibitor and therefore acts as a vasodilator In this prospective study 7 female patients with systemic sclerosis were enrolled: all of them had digital ulcerations and Raynaud’s phenomenon treatment with calcium channel inhibitors was ineffective dosage of sildenafil was 50-75mg per […]
Exogenous Ochronosis
Friday, December 13th, 2013Endogenous ochronosis (also called alcaptonuria) is a rare autosomal regressive disorder where there is enzymatic deficiency of homongentisic acid oxydase (AHG). This results in accumulation of AHG which is oxydized and polymerized in a substance close to melanin called benzoquinone acetic acid (ABQA). Its accumulation in the skin results in the clinical pigmentation. The […]
Members from Kazakhstan
Wednesday, November 27th, 2013Almaty Assel SATVALDINOVA MD
Vitiligo (For Professionals)
Friday, November 1st, 2013Vitiligo (For Professionals) Vitiligo affects around 1% of the population and is more visible in darker races. It is important to follow these steps: 1. See a dermatologist: -to confirm the diagnosis. -to classify the vitiligo: extent and distribution. -to ascertain its behaviour (stable for 6 months or evolutive?) -to follow an algorythm of treatment […]
Melanoma Detection in Children
Friday, November 1st, 2013Melanoma often goes undetected, especially in children. Indeed, because of its lower incidence there is often a low index of suspicion. Melanoma detection is a well-established science and the ABCDE criteria is a well established technique (combining wth dermoscopy if possible). Here is what the criteria stand for: A for Asymmetry B for Border irregularity […]
Members from Greece
Wednesday, October 30th, 2013Athens Maria KOSTAKI MD
Members from Nicaragua
Tuesday, October 22nd, 2013Managua Karla Maria ULOA DIAZ MD
Hydroquinone toxicity
Thursday, October 10th, 2013Short term and long term issues are described Short-term: Exogenous ochronosis. It is a possible side effect from prolonged use of hydroquinone, especially at concentrations higher than 4% It has also been described for resorcinol, phenols (such as rhododenol), oral antimalarials. It is due to inhibition of homogentisic acid by hydroquinone. On histology, the following […]
The problem with the skin whitening market
Tuesday, October 8th, 2013In some societies, skin colour is seen as important in social positioning. It is a common problem in darker skin types (IV to VI). The lighter the skin the better. In India it can determine the perceived “caste” to which an individual would belong. As a historical feature of interest, in Victorian times it was […]
About acne in adult females
Friday, October 4th, 2013Adult female acne: a new paradigm. Dréno B, Layton A, Zouboulis CC, López-Estebaranz JL, Zalewska-Janowska A, Bagatin E, Zampeli VA, Yutskovskaya Y, Harper JC. J Eur Acad Dermatol Venereol. 2013 Sep;27(9):1063-1070. doi: 10.1111/jdv.12061. Epub 2013 Jan 10. Adult female acne is a problem. Indeed 12% of females at age 40 still have acne. Most have […]
