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How does Cryotherapy work ?
Sunday, March 23rd, 2014Cryotherapy is a mostly destructive method and therefore biopsies tend to be less reliable but it does act through other mechanisms: direct injury: location: center of the lesion when: acts when the lesion is frozen vascular injury: location: periphery of the lesion when: acts upon thawing (reheating) of the lesion apoptosis: location: periphery of the […]
Etanercept (Enbrel) in the Treatment of Psoriasis
Sunday, March 23rd, 2014Etanercept is a fusion protein consisting of two tumor necrosis factor (TNF) receptors linked to the Fc protein of human immunoglobulin (IgG). It works by inhibiting the pro- inflammatory action of TNF in psoriasis. Patients inject the medication subcutaneously, with dosing either at 50 mg weekly (either as a single dose or divided into two […]
Seborrheic Dermatitis: When Conventional Treatments Fail
Saturday, March 22nd, 2014Systematic review of oral treatments for seborrheic dermatitis. Gupta AK, Richardson M, Paquet M. J Eur Acad Dermatol Venereol. 2014 Jan;28(1):16-26. doi: 10.1111/jdv.12197. Epub 2013 Jun 26. Seborrheic dermatitis (SD) is a common inflammatory disorder which affects: the scalp where it creates flaking of the skin or what is known as common dandruff (Pityriasis capitis). […]
Understanding Acne Vulgaris Through Research
Saturday, March 22nd, 2014Outline: Acne Vulgaris – New Insights From The Bench To The Clinic + overstimation of the risks of oral isotretinoin Recent advances in acne research have allowed a better understanding of the pathogenesis and etiological factors associated with acne: sebum overproduction by sebaceous glands is influenced by: dihydrotestosterone (DHT) Insulin-like Growth Factor (IGF)-1 PPAR ligands […]
Alopecia Areata: Measuring Disease Activity
Friday, March 21st, 2014Serum granulysin as a possible key marker of the activity of alopecia areata. Ono S, Otsuka A, Yamamoto Y, Kataoka TR, Koyanagi I, Miyachi Y, Kabashima K. J Dermatol Sci. 2014 Jan;73(1):74-9. doi: 10.1016/j.jdermsci.2013.08.009. Epub 2013 Sep 2. Alopecia areata (AA) is an auto-immune inflammatory dermatosis of the scalp resulting in non-scarring rounded patches of […]
The Role of Periostin in Aging
Thursday, March 20th, 2014The matricellular protein periostin contributes to proper collagen function and is downregulated during skin aging. Egbert M1, Ruetze M2, Sattler M1, Wenck H1, Gallinat S1, Lucius R3, Weise JM4. J Dermatol Sci. 2014 Jan;73(1):40-8. doi: 10.1016/j.jdermsci.2013.08.010. Epub 2013 Sep 3. Skin aging can be seen: on the epidermis by changes in texture and color. in […]
Does Rosacea become worse with time ?
Monday, March 3rd, 2014Subtypes 1, 2 and 3 have different upregulated genes. However there is a 20-30% overlap in the similarity of the genes being upregulated. Rosacea can be divided into two distinct forms; In the typical form, rosacea can progress from subtypes 1, 2 and 3. But not necessarily as we know that there are genetic similarities, […]
Conferences 2024
Wednesday, January 29th, 2014American Academy of Dermatology (AAD) Annual Meeting San Diego, CA, USA 8 – 12 March www.aad.org
Chronic Urticaria (For Professionals)
Wednesday, January 1st, 2014Chronic Urticaria (For Professionals) Chronic urticaria is a clinical sign of wheals appearing for more than 6 weeks. Numerous causes are identified and sometimes and auto-immune condition is found. If no cause is found which ranges from 25% to 75% of cases, autologous serum skin testing can be done, followed by dosing of anti-FCeRI antibodies […]
Oral Antidiabetic Drugs in Dermatology
Wednesday, January 1st, 2014Metformin in dermatology: an overview. Badr D, Kurban M, Abbas O. J Eur Acad Dermatol Venereol. 2013 Nov;27(11):1329-35. doi: 10.1111/jdv.12116. Epub 2013 Feb 26. Metformin is an oral hypoglycaemic agent. It acts by decreasing hepatic glucose output and increases the glucose utilization by muscles and adipocytes (increase in sensitivity to insulin) It also has a […]
