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Biologic Therapy for Psoriasis: Paradoxical Reactivation of Psoriasis on Infliximab
Saturday, October 11th, 2014Infliximab is an anti-TNF biologic It is used in the treatment of rheumatoid arthritis, psoriasis and inflammatory bowel disease A case report from Spain: 32 year old female known for Crohn’s disease no response to mesalazine and systemic corticosteroids was subsequently put on infliximab at a dosage 5mg/kg for a duration of 10 years she […]
Treating Viral Warts with Tuberculosis-derived Proteins ?
Saturday, October 11th, 2014In this Indian study, protein samples of Mycobacterium Tuberculosis (similar to the one used in the Mantoux screening test) were used: PPD – purified derivative of M.Tuberculosis 10IU PPD 0,1ml indication: facial and palmoplantar warts or more than 15 (no mention of genital warts) 2.5 IU (or TU: Tuberculin Units) on left forearm 2.5 IU […]
Facebook and Twitter in Dermatology
Saturday, October 11th, 2014Facts about facebook Most visited website in the world with 1.3 billion users 72 % visit the website at least once a month 829million daily users Duration of each visit lasts on average 21 minutes Facts about Twitter 1 billion users 550 million accounts BUT 44% never tweeted 271million monthly users average time per month […]
Mobile “apps” in Dermatology
Saturday, October 11th, 2014What “apps” are available and do they work ? At the time of this presentation about 1 million apps are available app store 50 billion downloads 17000 apps are health-related – evidence about their reliability is mostly lacking. They are projected to generate $26 billion revenue in 2017 In 33% physicians are NOT involved in […]
Treatment of Childhood Acne
Friday, October 10th, 2014Incidence of Acne in the first 20 years of life: -3% of affected individuals are neonates -6% in childhood (pre-adolescents) -91% in teenagers (adolescents…predictably) Thorough examination must be done in children to rule out differential diagnosis: -keratosis pilaris -miliara -perorificial dermatatis -pomade acne (cosmetic use) -flat warts -molluscum contagiosum Scarring is a complication […]
The Anti-Aging Effects of Hyaluronic Acid: Beyond Fillers
Friday, October 10th, 2014Age-related changes are due to many factors influencing the structure of the epidermis (texture changes) as well as changes in the dermis (loss of volume). The following study shows the role of hyaluronic acid (HA), BOTH large and small fragments in Epidermal age related skin changes. This study shows that topical application of small HA […]
Faster Wound Healing in Psoriasis and Why ?
Friday, October 10th, 2014Central to that is calcium regulation which allows changes in cellular differentiation. The N-methyl-D-aspartate receptor (NMDAR) is important for this and is abnormally expressed in psoriasis lesions. In this study, the speed of wound healing is suggested to be faster in psoriasis wounds as compared with wounds of unaffected individuals. Psoriasis shares many things in […]
Androgenetic Alopecia Treatment with Platelet Rich Plasma (PRP)
Friday, October 3rd, 2014Androgenetic alopecia is an often hereditary condition with thinning of the hair into vellus hairs which occurs in males and females according to a male pattern (Hamilton classification) or a female pattern (ludwig classification) It is psychologically devastating and treatments include topical (minoxidil), oral (finasteride) treatments sometimes so ineffective that the only solution is wearing […]
Skin Manifestations of Mixed Connective Tissue Disease (MCTD) (For Professionals)
Wednesday, October 1st, 2014One of the autoimmune systemic diseases which have extensive skin manifestations is mixed connective tissue disease or MCTD. This disorder is a combination of other autoimmune diseases such as lupus erythematosus, systemic sclerosis and polymyositis. The cause of this disorder is not completely known but is stipulated to be an effect of one’s immune system […]
Fighting Skin Aging by Targeting the Degradation of Collagen by Collagenase
Tuesday, September 30th, 2014Skin aging (ageing) concerns the skin, in the epidermis where it is responsible for texture changes. However the most visible effect of aging is loss of volume in the dermis. In the dermis intact collagen fibers (as well as hyaluronic acid) play an important structural role in its volume. The visible changes in aging are […]
