Articles
Phototherapy-Induced Immunosuppressive Effects
Friday, July 1st, 2011Topical photodynamic therapy is immunosuppressive in humans. Matthews YJ, Damian DL Br J Dermatol 2009 Oct 26 In this Australian study, investigation of immunosuppression after photodynamic therapy was done with the Mantoux test (delayed-type hypersensitivity responses to tuberculin purified protein derivative) Introduction: Visible light irradiation following application of a photosensitizer (topical photodynamic therapy; PDT) is […]
Features Of Atopic Dermatitis In Adults
Sunday, May 1st, 2011Features Of Atopic Dermatitis In Adults Atopic dermatitis in older patients: particular points. Katsarou A, Armenaka MC. J Eur Acad Dermatol Venereol. 2010 Jun 21. Atopic Dermatitis (AD) is increasing in its frequency mostly due to the phenomenal increase in atopy we have seen in the last 20 years. Therefore more and more adults are […]
Thalidomide « the First Biologic Drug »
Sunday, March 27th, 2011Thalidomide and Analogues: Potential for Immunomodulation for Inflammatory and Neoplastic Dermatologic Disorders. Ladizinski B, Shannon E, Sanchez M, Levis W. J. Drugs Dermatol. 2010; 9 (7): 814-826. Thalidomide was introduced in 1953 and was prescribed over-the-counter against nausea in pregnant women. It resulted in serious malformations and the drug was rapidly banned. Because t of […]
Matchsticks On Dermoscopy = A Clue to Netherton’s Syndrome
Sunday, February 27th, 2011Matchsticks On Dermoscopy = A Clue to Netherton’s Syndrome ‘Matchstick’ eyebrow hairs: a dermoscopic clue to the diagnosis of Netherton syndrome. Goujon E, Beer F, Fraitag S, Hovnanian A, Vabres P. J Eur Acad Dermatol Venereol. 2009 Oct 15. Netherton’s syndrome is an automal recessive skin condition (SPINK 5 frameshift mutations) caracterized by: ichthyosiform erythroderma […]
Update on Acne and Diet
Thursday, January 27th, 2011Diet and acne. Bowe WP, Joshi SS, Shalita AR. J Am Acad Dermatol. 2010 Jul;63(1):124-41. It is common for dermatologists to dispell myths that acne wouldn’t be related to diet. Controversy exists in this domain due to the fact that a lot of the initial myths advocating an implication of certain diets (chocolate, sweets, fats) […]
Cured of HIV Infection by a Bone Marrow Transplantation
Thursday, December 16th, 2010Evidence for the cure of HIV infection by CCR5{Delta}32/{Delta}32 stem cell transplantation. Allers K, Hütter G, Hofmann J, Loddenkemper C, Rieger K, Thiel E, Schneider T. Blood. 2010 Dec 8. This revolutionary article shows a cure of a patient with leukemia and HIV infection (1). A 42 year old American male received a bone marrow […]
Long-Pulsed ND-YAG Laser for Telangiectasia Treatment
Wednesday, December 1st, 2010Clinical experience in the treatment of different vascular lesions using a neodymium-doped yttrium aluminum garnet laser. Civas E, Koc E, Aksoy B, Aksoy HM. Dermatol Surg. 2009 Dec;35(12):1933-41. This article is interesting because it highlights the efficacy of the treatment of telangiectasia and spider angiomas. Long pulsed NDYAG has mainly been shown to be effective […]
Treatment found for Dystrophic Epidermolysis Bullosa ?
Wednesday, August 18th, 2010Bone Marrow Transplantation for Recessive Dystrophic Epidermolysis Bullosa Wagner J., Ishida-Yamamoto A., McGrath J., Hordinsky M., Keene R., Riddle M., Osborn M., Lund T., Dolan M., Blazar B, Tolar J. N Engl J Med 2010; 363:629-639. August 12, 2010 Epidermolysis Bullosa is a genetic condition in most cases and different mutations affect the epidermis, basal […]
Recurrence of Melanocytic Naevi (Mole) is low after biopsy
Tuesday, July 27th, 2010Low rates of clinical recurrence after biopsy of benign to moderately dysplastic melanocytic nevi (DN). Goodson AG, Florell SR, Boucher KM, Grossman D. J Am Acad Dermatol. 2010 Apr;62(4):591-6. Epub 2009 Dec 16. Clinical fear of melanoma leads to complete excision of dysplastic naevi (DN) when biopsy reveals postive margins. However this study opens the […]
Combination creams for acne-with an antibiotic or a weak retinoid?
Tuesday, June 29th, 2010Study of the efficacy, tolerability, and safety of 2 fixed-dose combination gels in the management of acne vulgaris. Zouboulis CC, Fischer TC, Wohlrab J, Barnard J, Alió AB. Cutis. 2009 Oct;84(4):223-9. Combination creams for the treatment of moderate acne vulgaris are the new trend in therapeutic dermatology. The big issue of these products has been […]
