Professionnels « Globale Dermatologie

How the action of Cyclosporine helps in understanding anti-Il17 and anti-Il23 biologics

samedi, décembre 13th, 2014

When looking at psoriasis lesions, numerous T cells are present. In 1979, cyclosporine was shown to act on psoriasis as a T cell suppressor. Nevertheless, at that time but it was also shown to have an antiproliferative action on keratinocytes. Result: the biological action (cytokine inhibition) was overlooked. T cells are stimulated by antigen presenting […]

Posted in Notes de congrès/conférences |

Psoriasis is enhanced by high fat diet and a possible explanation to why

samedi, décembre 13th, 2014

Obesity is a public health problem It is also associated with psoriasis and the Th17 cell plays a role There is a link between Body Mass Index (BMI) and the prevalence of psoriasis: however the pathophysiological reason to this link is unknown…however this study tries to give an explanation The authors used a mouse obese […]

Posted in Notes de congrès/conférences |

Maintaining Youthful Skin: Perhaps a Massage is what Benchmark Research Suggests

vendredi, décembre 12th, 2014

The skin is routinely exposed to mechanical stimuli such as: stretching, contraction, compression, torsion Cyclical stretching : increases secretion of humoral factors and proteolytic enzymes by activating inflammatory signaling pathways in keratinocytes and fibroblasts induces degradation of the extracellular matrix …the response to it depends on the nature of the stimulus and its duration Methods […]

Posted in Notes de congrès/conférences |

Semi permanent Make-up removal with Lasers

vendredi, décembre 12th, 2014

Semi permanent tattoos are often used to alleviate tedious daily make-up but they also, like other tattoos can become cosmetically unacceptable. Treatment: Available classical treatments include, surgery, dermabrasion but both induce scarring which is not acceptable for patients who are looking for a cosmetic procedure to correct another one. Q-Switched lasers have been tried and […]

Posted in Notes de congrès/conférences |

Tuberous Sclerosis Treatment with topical Rapamycin: Beyond treating Facial Angiofibromas

vendredi, décembre 12th, 2014

Tuberous Sclerosis (TSC) is a multisytemic condition characterized by numerous skin signs (shagreen patch, ash leaf macules…). Of these, hypomelanotic macules are the most frequent sign and are present in 90% of patients with TSC. (Macules have to be 3 or more in number to fit in the diagnosis of TSC). The cause of TSC […]

Posted in Notes de congrès/conférences |