Le thalidomide: « le plus ancien des biologiques »
Thalidomide and Analogues: Potential for Immunomodulation for Inflammatory and Neoplastic Dermatologic Disorders. Ladizinski B, Shannon E, Sanchez M, Levis W. J. Drugs Dermatol. 2010; 9 (7): 814-826. Thalidomide was introduced in 1953 and was prescribed over-the-counter against nausea in pregnant women. It resulted in serious malformations and the drug was rapidly banned. Because t of…