Management of psoriasis vulgaris and multiple sclerosis with fumaric acid. Gkalpakiotis S, Arenberger P, Gkalpakioti P, Meluzinova E, Chandran D, Arenbergerova M. J Am Acad Dermatol. 2014 Mar;70(3):e60-1. doi: 10.1016/j.jaad.2013.10.031. Fumaric Acid is a big thing in Germany. It is used in the management of psoriasis under the brand name Fumaderm It also seems to…
Toenail onychomycosis treated with a fractional carbon-dioxide laser and topical antifungal cream. Lim EH, Kim HR, Park YO, Lee Y, Seo YJ, Kim CD, Lee JH, Im M. J Am Acad Dermatol. 2014 May;70(5):918-23. doi: 10.1016/j.jaad.2014.01.893. Epub 2014 Mar 18. Nail onychomycosis is a infectioyus fungal infection which typically affects the toenails. Although present in…
Reagents inducing epidermal proliferation also induce pigmentation: induction of keratinocyte proliferation as a novel strategy for the treatment of vitiligo. Wu CS, Komine M, Fujimoto S, Ohmatsu H, Kikuchi K, Tada Y, Yu HS, Ohtsuki M, Tamaki K. J Dermatol Sci. 2013 Oct;72(1):66-8. doi: 10.1016/j.jdermsci.2013.05.005. Epub 2013 Jun 18. No abstract available. Vitiligo affects 1%…
Duration of efficacy increases with the repetition of botulinum toxin A injections in primary palmar hyperhidrosis: a study of 28 patients. Lecouflet M, Leux C, Fenot M, Célerier P, Maillard H. J Am Acad Dermatol. 2014 Jun;70(6):1083-7. doi: 10.1016/j.jaad.2013.12.035. Epub 2014 Mar 12. Excessive sweating of the palms or Palmar Hyperhidrosis is a psychologically devastating…
Increased risk of diabetes mellitus in relation to the severity of psoriasis, concomitant medication, and comorbidity: a nationwide population-based cohort study. Lee MS, Lin RY, Lai MS. J Am Acad Dermatol. 2014 Apr;70(4):691-8. doi: 10.1016/j.jaad.2013.11.023. Epub 2014 Jan 9. Introduction: Diabetes Mellitus doesn’t necessarily occur in patients with psoriasis but some clinical caracteristics as well…
A randomized, active- and placebo-controlled study of the efficacy and safety of different doses of dutasteride versus placebo and finasteride in the treatment of male subjects with androgenetic alopecia. Gubelin Harcha W, Barboza Martínez J, Tsai TF, Katsuoka K, Kawashima M, Tsuboi R, Barnes A, Ferron-Brady G, Chetty D. J Am Acad Dermatol. 2014 Mar;70(3):489-498.e3.…
A role of placental growth factor in hair growth. Yoon SY, Yoon JS, Jo SJ, Shin CY, Shin JY, Kim JI, Kwon O, Kim KH. J Dermatol Sci. 2014 May;74(2):125-34. doi: 10.1016/j.jdermsci.2014.01.011. Epub 2014 Feb 6. Hair growth is a process which requires the presence of a hair follicle and a functional dermal papilla (DP).…
Demodicosis is a disease in itself due to the presence of the mite Demodex folliculorum first classied as such in 1842 by the German dermatologist Carl Gustav Theodor Simon. It is easily confused with Rosacea (Acne Rosacea) because the latter, although considered to be associated with the presence of the mite, is controversial and an…
Propionibacterium acnes: an update on its role in the pathogenesis of acne. Beylot C, Auffret N, Poli F, Claudel JP, Leccia MT, Del Giudice P, Dreno B. J Eur Acad Dermatol Venereol. 2014 Mar;28(3):271-8. doi: 10.1111/jdv.12224. Epub 2013 Aug 1. P. acnes is a bacteria whic has a strong proinflammatory activity and targets molecules involved in…
Il-17 targeting is the new trend in the biologic systemic treatment of psoriasis. Ustekinumab (Stelara) is the main one used today in that sense. Secukinumab: is a fully anti-interleukin-17A monoclonal antibody is (at the time of publishing this article) the latest Il-17A drug to have exited phase III trials. The results out of two studies…
