Daily Archives: dimanche 14 décembre 2014

A tool to study Rhodenol (Rhododendrol) induced leucoderma (Vitiligo-like lesions)

Rhododendrol (Rhododenol, RD) created a big problem in Japan, when 14000 induced cases of vitiligo-like lesions were reported. It is known that Rhodoendol is cytoxic against melanocytes in a Tyrosinase dependent way cytotoxicity The authors suggest a new mouse model for the study of this effect: hk14-scf/HRM Tg Mice become albino (fully depigmented) through suppression…

Protection against Ultraviolet Light (UVB) with Phloretin Sulfate

The phenolic compound phloretin: is a member of dihydrochalcones is found in apples and apple juice Phloretin 3,3 disulfonate (P33D) is obtained after its sulfonation with sulfuric acid Pure concentrated Phloretin sodium sulfonate was added to Human Cell cultures which were irradiated with UVB 20 mJ/cm2 Results show that reduced amounts of P33D were found…

Molecules AGAINST Tanning in the cosmetic world

In early 20th century Europe, it was considered a mark of « low-class », as it was assimilated with outdoor professional activities. It is quite fashionable to tan in Western societies (Europe and North America), but is definitely not fashionable in Asia. Tanning is a process induced by ultraviolet light and is a protective mechanism to shield…