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Nouvelles substances dépigmentantes

New Depigmenting substances: N-acetyl glucosamine Artocarpanone 4-n-butylresorcinol (rucinol) Ursolic Acid Anthraquinones Cinnamic Acid Macelignan Gallic Acid Glycine Isopanduratin A and 4-Hydroxypanduratin A Kurarinol, Kurarinidol and Trifolirhizin Pycnogenol 8% topical indomethacin cream Selina dien-8-one Taxifolin DeoxyArbutin and its second generation derivatives Hydroperoxy Traxastane t; type Triterpene Piceatannol Handog E. Brown Spots: Melasma Updates.2012 (02) – 20th…

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Notes de congrès/conférences, Produits dépigmentants "traditionnels"

Nouvelles substances dépigmentantes

New Depigmenting substances: N-acetyl glucosamine Artocarpanone 4-n-butylresorcinol (rucinol) Ursolic Acid Anthraquinones Cinnamic Acid Macelignan Gallic Acid Glycine Isopanduratin A and 4-Hydroxypanduratin A Kurarinol, Kurarinidol and Trifolirhizin Pycnogenol 8% topical indomethacin cream Selina dien-8-one Taxifolin DeoxyArbutin and its second generation derivatives Hydroperoxy Traxastane t; type Triterpene Piceatannol Handog E. Brown Spots: Melasma Updates.2012 (02) – 20th…

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Notes de congrès/conférences, Produits dépigmentants "traditionnels"

Lèpre: Prévention

Prevention: primary: no vaccine available Vaccination against tuberculosis (TBC) also called BCG  (Bacille Calmette Guerin against tuberculosis) has some effect secondary=early diagnosis and treatment: chemoprophylaxis (treatment of subclinical leprosy) (destined to those in potential contact) and immunoprophylaxis: single dose of rifampicine 300mg-600mg according to weight tertiary: prevention of disability leprosy (Hansen’s Disease) and TBC BCG…

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Substances dépigmentantes existantes

They act through: Tyrosinase Inhibition Inhibitors of Inflammation-induced Melanogenic Response Peroxidase inhibition Product Reduction and ROS (Radical Oxygen Scavengers)   Tyrosinase inhibition hydroquinone 4-hydroxyanisole 4-S-CAP and derivatives Arbutin Aloesin Azelaic Acid Kojic Acid Ellagic Acid Resveratrol Oxyeresveratrol Licorice Extract Lactic Acid   Inhibitors of Inflammation Induced Melanogenic Response Chamomille Corticosteroids Gliabridin Tranexamic Acid   Peroxidase…

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Notes de congrès/conférences, Produits dépigmentants "traditionnels"

Melasma (Chloasma) (Masque de Grossesse): éléments diagnostics, épidémiologiques et importance de la protection solaire

Skin color is determined by: The type of melanin The amount of melanin in melanocytes The distribution pattern in surrounding keratinocytes   The term melasma comes from Greek melas: black Etiology: The exact cause is unknown but some factors play a role Ultraviolet light (UV) genetic factors thyroid disturbances cosmetics hormonal factors (in females) Epidemiology…

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Vitiligo: Traitement par combinaison de modalités thérapeutiques

Dr Christophe HSU – dermatologist. Geneva, Switzerland Medical Repigmentation treatments consist of: medical: topical (tacrolimus, pimecrolimus, topical corticosteroids…(calcipotriène, pseudocatalase, piperine)), systemic (pulse steroids…) -UV (Ultraviolet)-based therapy: Narrow Band UVB (NBUVB) is the mainstay of treatment. PUVA (Psoralen + UVA is also used but is more complicated (and less effective). Let us consider the following combination…

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Pigmenter la peau avec des injections de Afamelanotide (Melanotan) (Scenesse)

Indications: Photodermatoses Could be used as a “lifetstyle” drug to darken (tan) the skin. Afamelanotide (Melanotan) (Scenesse): induces melanin deposition (Alpha MSH (Melanocyte Stimulating Hormone) analogue) is given subcutaneously in two injections of 20mg 60 days apart. Its effect is independent from UV (Ultraviolet) light exposure or dosage It increases tolerance to artificial light Contributors:…

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Quoi de Neuf en Photodermatologie ?

-Polymorphous Light Eruption (PMLE): -appearance more papular in darker skin -PML patients are more resistant to UV-induced immunosuppression. Explains the “Hardening Concept”: desentisization treatment with UV light: enables immunotolerance -Voriconazole (antifungal): has been shown to induce developement of erythema, lentigenes, squamous cell carcinoma and melanoma –Vemurafenib (BRAF inhibitor used for the treatment of metastatic melanoma):…

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