Other articles deal with this issue however we can say here that lasers play a limited role: They are only indicated in the treatment of dermal melasma (chloasma, pregnancy mask). Even in this indication, the response is unpredictable* and the pigmentation tends to recur. Response to treatment has been reported for the following lasers (non-exhaustive…
DetailsTranexamic acid is an antifibrinolytic which inhibits the conversion of plasminogen to plasmin. It has an antiallergic and antiinflammatory action. It might be effective in the treatment of melasma (chloasma, pregnancy mask): However tranexamic acid is in its inital stages and over the long run, the good results in the few reports* might not be…
DetailsHydroquinone is the Gold Standard for treating Melasma (Chloasma, Pregnancy Mask). Numerous concentrations are used but a concentration of 4% in practice begins to be effective (and to have side-effects). Side effects include: erythema burning exogenous ochronosis confetti-like depigmentation In practice it is safe to use at 4% when closely supervised medically. Contributors: Dr Christophe…
DetailsHydroquinone is the Gold Standard for treating Melasma (Chloasma, Pregnancy Mask). Numerous concentrations are used but a concentration of 4% in practice begins to be effective (and to have side-effects). Side effects include: erythema burning exogenous ochronosis confetti-like depigmentation In practice it is safe to use at 4% when closely supervised medically. Contributors: Dr Christophe…
DetailsIn practice, when a patient is seen during a consultation, for a pigmentation problem, it is labelled “facial melanosis”. The most frequent cause of facial melanosis is chloasma (melasma, pregnancy mask) When in doubt should we do a biopsy on the face ? Yes, sometimes. Here are some other causes of facial melanosis: Leprosy when…
DetailsIn practice, when a patient is seen during a consultation, for a pigmentation problem, it is labelled “facial melanosis”. The most frequent cause of facial melanosis is chloasma (melasma, pregnancy mask) When in doubt should we do a biopsy on the face ? Yes, sometimes. Here are some other causes of facial melanosis: Leprosy when…
DetailsPigments There are two types of pigments (melanin) which determine skin colour in caucasians: Eumelanin: Has a photoprotective action Acts as a physical and chemical filter to light Absorbs free radicals in response to sun exposure Pheomelanin Is found most often in red-haired individuals Has a photoaggressive action Produces free radicals in response to sun…
DetailsDermatology in Infectious Diseases – Table of Contents
Hansen’s Disease (Leprosy):
Cysteamine cream as a new skin depigmenting product Hsu C.1, Ahmadi S.2, Pourahmad M.3, Ali Mahdi H.4,. 1 Centre Medical du Lignon Geneva, Switzerland 2, 3 : Jahrom Universty Medical school, Jahrom, Iran. 4: Global Dermatology Information Portal, Royal Bahrain Hospital, Bahrain Cysteamine hydrochloride (β-mercaptoethylamine hydrochloride) has been known to be a potent…
DetailsTopical isonicotinic acid hydrazide (isoniazid) as a new skin depigmenting compound Ahmadi S.1, Pourahmadi M.1, Aslani F.S.2, Kasraee B.3 1 Jahrom University of Medical Sciences, Jahrom, Iran 2 Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran 3 Scientis Pharma SA, Geneva, Switzerland Isonicotinic acid hydrazide (isoniazid) is the most commonly used antituberculosis medication. This…
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