Vitiligo (For Professionals) Vitiligo affects around 1% of the population and is more visible in darker races. It is important to follow these steps: 1. See a dermatologist: -to confirm the diagnosis. -to classify the vitiligo: extent and distribution. -to ascertain its behaviour (stable for 6 months or evolutive?) -to follow an algorythm of treatment…
DetailsMelanoma often goes undetected, especially in children. Indeed, because of its lower incidence there is often a low index of suspicion. Melanoma detection is a well-established science and the ABCDE criteria is a well established technique (combining wth dermoscopy if possible). Here is what the criteria stand for: A for Asymmetry B for Border irregularity…
DetailsShort term and long term issues are described Short-term: Exogenous ochronosis. It is a possible side effect from prolonged use of hydroquinone, especially at concentrations higher than 4% It has also been described for resorcinol, phenols (such as rhododenol), oral antimalarials. It is due to inhibition of homogentisic acid by hydroquinone. On histology, the following…
DetailsIn some societies, skin colour is seen as important in social positioning. It is a common problem in darker skin types (IV to VI). The lighter the skin the better. In India it can determine the perceived “caste” to which an individual would belong. As a historical feature of interest, in Victorian times it was…
DetailsAdult female acne: a new paradigm. Dréno B, Layton A, Zouboulis CC, López-Estebaranz JL, Zalewska-Janowska A, Bagatin E, Zampeli VA, Yutskovskaya Y, Harper JC. J Eur Acad Dermatol Venereol. 2013 Sep;27(9):1063-1070. doi: 10.1111/jdv.12061. Epub 2013 Jan 10. Adult female acne is a problem. Indeed 12% of females at age 40 still have acne. Most have…
DetailsEffect of tranexamic acid on melasma: a clinical trial with histological evaluation. Na JI, Choi SY, Yang SH, Choi HR, Kang HY, Park KC. J Eur Acad Dermatol Venereol. 2013 Aug;27(8):1035-9. doi: 10.1111/j.1468-3083.2012.04464.x. Epub 2012 Feb 13. Melasma is associated with an increased density of blood vessels Tranexamic Acid (TA) acts on inhibition of plasmin…
DetailsExtra-facial melasma: clinical, histopathological, and immunohistochemical case-control study. Ritter CG, Fiss DV, Borges da Costa JA, de Carvalho RR, Bauermann G, Cestari TF. J Eur Acad Dermatol Venereol. 2013 Sep;27(9):1088-94. doi: 10.1111/j.1468-3083.2012.04655.x. Epub 2012 Jul 24. Melasma is a common pigmentary disorder in women in their childbearing years taking the oral contraceptive pill. Its location…
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