Sweet’s syndrome is a neutrophilic dermatosis of unknown etiology which presents as “mountain-like” papulesand is often accompanied by systemic symptoms such as fever, myalgia, asthenia and malaise. The cause is often not found but includes: infections (respiratory, gastrointestinal), autoimmune conditions (lupus, rheumatoid, arthritis), vaccination, neoplasia (solid and non solid), drugs (NSAIDS, cotrimoxazole, antiiotics, carbamazepine…) pregnancy,…
DetailsVancomycin is an antibiotic used for intravenous treatment of bacterial infections, particularly hospital (nosocomial) acquired ones such as with Methicillin Resistant Staphlococcus Aureus (MRSA) infections, which are resistant to penicillin. Vancomycin is known to create neutropenia but the following case report reports the occurrence of a neutrophilic dermatosis mimicking cryptococcus. No organism was found and…
DetailsBasal Cell Carcinoma is know to be physiopathologically generated by an activation of the sonic hedgehog pathway. Vismodegib is an inhibitor of smoothened (SMO*) and is proposed as an adjuvant therapy before radiotherapy here after a successful case report: it was used as a therapy for basal cell carcinoma (BCC) and squamous cell carcinoma (SCC)…
DetailsLichen Striatus is a dermatosis along Blaschko lines and its etiology is unknown. It would occurr secondarily to a cytotoxic reaction because of a stimulation of the immune system. The authors report lichen striatus occurring after etanercept (50mg/d) in a 70 year old patient treated for rheumatoid arthritis. For full access to the free article…
DetailsThe second EADV clinico-pathological course using virtual dermatopathology will be held October 9th, at the 23rd Congress of the EADV in Amsterdam. www.eadvamsterdam2014.org The faculty is an international team of speakers: Ellen Mooney, Chair, Gürkan Kaya and Ismini Vassilaki, Co-Chairs, Christina Mitteldorf and Jacqueline Junkins-Hopkins. Please note: Participants must sign up for the course…
DetailsIsotretinoin remains the gold standard in the treatment of Acne Vulgaris especially since tolerable doses nowadays focus on low doses. However, even with this, patients can have difficulty tolerating them because of the occurrence of side effects such as xerosis of the skin and mucous membranes. Also, even here, isotretinoin can have adverse effect on…
DetailsAlthough tattoos are fairly easy to do they can be a challenge to remove. Why are lasers used for tattoo removal ? In the past tattoo removal involves tissue-destructive techniques including excision/grafting, dermabrasion, cryosurgery and electrosurgery. Although effective at removing the tissue pigments, these techniques often cause scaring, textural changes, keloids and permanent dyschromia. Lasers…
DetailsAlbinism is a rare genetic condition affecting around 1 out of 17000 individuals (can vary geographically). Albinism is characterized by severe and handicapping deficits in the visual system in association with a most variable hypopigmentation phenotype: visual defects include: foveal hypoplasia, reduced pigmentation of retinal pigment epithelium cells, misrouting of the optic nerves at the…
DetailsMelasma (Chloasma, Pregnancy Mask) is a common pigmentary condition and although it occurs more often in females and that hormonal factors may play a role, it is still incompletely understood. Clinically: In the lesions, telangiectasia (dilated broken blood vessels), tend to be present and melasma lesions have more vascularization when compared with the perilesional skin.…
DetailsUp to 100 million individuals may be infected by the dengue virus each year. The virus is transmitted through arthropod bites (usually mosquitoes). Population increase makes control of mosquito population difficult as breeding sites (stagnant waters) are more numerous and less detectable (roofs…). Infection ranges from asymptomatic infection to dengue fever with/without hemorrhagic fever and…
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