Acide Azélaïque (AZA)
AZA is a dicarboxylic acid synthesized by the fungus Malassezia fur fur. Cutaneous infection with this fungus causes a significant and long lasting depigmentation in the affected areas, which is believed to be induced by AZA. AZA is an inhibitor of the enzyme tyrosinase, the key melanogenic enzyme in melanocytes. When applied to the skin…