Topical steroids in dermatology: the story behind it

The use of steroids in dermatology was initiated by two American New-York based dermatologists: Marion Sulzberger and Victor Witten. Topical steroids: early topical preparations containing cortisone acetate were surprisingly ineffective HYDROcortisone acetate was made available (“Compound F” by Merck): It was combined 25mg/g with an ointment base…and became moderately effective initially for Atopic Dermatitis. Results…