Topical steroids in dermatology: the story behind it

The use of steroids in dermatology was initiated by two American New-York based dermatologists: Marion Sulzberger and Victor Witten. Topical steroids: early topical preparations containing cortisone acetate were surprisingly ineffective HYDROcortisone acetate was made available (“Compound F” by Merck): It was combined 25mg/g with an ointment base…and became moderately effective initially for Atopic Dermatitis. Results…

Warts and Molluscum Contagiosum: How they were shown NOT to be bacterial in origin

In the early 20th century (1919)  two American dermatologists* sought to determine the origin of warts and molluscum contagiosum: To do this they curetted tissue from the 2 lesions and added saline.  after “mincing them”, they passed it through a filter to remove all bacteria (Berkefeld filter) They then auto-inoculated themselves and volunteers with the…