Piebaldism: rare but all dermatologists have heard this strange term during residency
- The use of steroids in dermatology was initiated by two American New-York based dermatologists: Marion Sulzberger and Victor Witten.
- Topical steroids:
- early topical preparations containing cortisone acetate were surprisingly ineffective
- HYDROcortisone acetate was made available (“Compound F” by Merck):
- It was combined 25mg/g with an ointment base…and became moderately effective initially for Atopic Dermatitis.
- Results were published in the Journal of Investigative Dermatology in 1952
- From here onwards, with increasingly effective formulas of steroids, the art of compounding preparations started to be lost…resulting in less lengthy prescriptions.
Source of information: Crissey JT el al. Dermatology and Dermatologists (2002). Parthenon Publishing
Related posts