Atopic Dermatitis: a Short Summary
- Acne scarring is a common complaint in acne patients. This is a visible sequlae of active acne and persists for a lifetime. Treatments can be costly and include chemical peels and fractionated CO2 laser therapy.
- This study measures the effect of adapalene in the treatment of acne scars
- Methods
- prospective study
- single-center, open-label, pilot study in subjects aged 18-50 (20 subjects, 11 male, 35,7 years old on average. On average facial acne had been present for 22.86 years and the scars for 19.26 years)
- The scars were graded moderate or severe facial atrophic acne scars (3-4 Goodmann-BBaron scale) and were of the following types: icepick, boxcar or rolling
- The study was done over a period of 24 weeks and measurements were done:
- at baseline
- on day 10
- at weeks 8, 16, 24
- Post-treatment follow up at 36 weeks and 48-72 weeks
- Assessment: Global scarring grade, investigator global assessment, subject global assessment as well as quality of life scores.
- Results
- The acne scars at baseline were moderate (in 60% of cases)
- At week 24, more than half of the subjects (55%) achieved a 1 (38.9%) to 2 (16.6%) grade change of acne scar severity.6-12 months after the treatment, the results were still maintained in 50% of subjects.
- IGA, SSA, subject satisfaction and quality of life scores (DLQI: Dermatology Life Quality Index all improved).
- Comment: No photographic assessment was done, no pictures were shown.
Contributors
Dr Christophe Hsu – dermatologist. Geneva, Switzerland
Source of information: 2014 (03) – Patel M, Improvement in atrophic scars by topical adapalene 0.3%. 72nd AAD (American Academy of Dermatology) Annual Meeting (Denver, CO, United States of America). Study was done by Galderma
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